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Genomic Data Quality: Connecting the Dots Between Bioinformatics and Physical Materials
Check out our AMP 2022 Corporate Workshop to learn more about our standardized approach to producing high-quality reference genomes from authenticated ATCC biological materials.
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Large-scale Manufacturing and Functional Assessment of Extracellular Vesicles
This is a talk presented at the American Exosome and RNA Conference that demonstrates a method for the isolation of high-quality EVs from large-scale batches.
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Towards Genome Authentication: The ATCC Genome Portal
This presentation highlights the importance of genomics data provenance and details how the ATCC Genome Portal addresses this issue.
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Advanced Drug-resistant Cell Models for Cancer Therapeutic Resistance Studies
In this workshop, we highlighted how state-of-the-art ATCC drug-resistant cancer cell models created by CRISPR gene-editing technology can facilitate the discovery of new types of therapeutics that overcomes drug resistance.
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Advancing Authentication through Credible Standards and Robust Next-generation Sequencing Workflows
In this workshop presentation, we discuss the importance of credible reference materials in microbial genomics with a particular focus on microbiome and phylogenetic studies. We also preview ATCC’s genome portal of high-quality assembled genomes for advancing the authentication of ATCC strains.
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ATCC Molecular Signature Panels - Powerful Tools for the Genomics Age
ATCC molecular signature panels focus on key components of cell signaling pathways such as EGFR, AKT, PI3K, PTEN, or p53. This presentation describes how we generated these panels using authenticated cell lines containing critical gene copy number changes and site mutations.
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Challenges and Solutions in the Development and Application of Microbiome Standards
In this collaborative discussion, microbiome experts discuss the hurdles that microbiome researchers face during each stage of the workflow, challenges and solutions in the development and application of standards, and current gaps and future trends in microbiome research.
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Data Provenance & Authenticity in Microbial Genomics
Watch the presentation to learn more about the importance of data provenance in genomics and ATCC’s approach to producing high-quality, authenticated reference genomes.
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Development of Fungal Mock Community Standards for Mycobiome Studies
In this presentation, we explore the development of fungal NGS standards for mycobiome research and demonstrate the utility of these standards in evaluating DNA extraction and sequencing methods for mycobiome analysis.
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Development of the PI3K Pathway Inhibitors - How to Choose the Right Cell Line
Mutations in several of the enzymes in the PI3K pathway have been implicated in the pathogenesis of several types of cancer. In this presentation, we discuss the development and application of several cell panels comprising tumor cell lines that feature mutations along the PI3K pathway.
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hTERT Immortalized Cell Lines - Unique Tools for Tissue-relevant Research
ATCC Human telomerase (hTERT) immortalized cell lines combine the in vivo nature of primary cells and the long culture life of continuous cell lines. This presentation provides an overview of the hTERT-immortalized cell line collection at ATCC.
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Induced Pluripotent and Mesenchymal Stem Cells - Cells with a Lot of Potential
ATCC has a wide selection of induced pluripotent and mesenchymal stem cells along with an array of associated culture media and reagents. This presentation provides an overview of the ATCC stem cell collection and describe how these resources can be used in cell biology studies.
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Making Sense Out of Microbiome Data
The complexities involved in metagenomics methods often result in the introduction of biases throughout the workflow, ultimately impacting data interpretation and reproducibility. This workshop highlights the importance of standards in facilitating assay standardization and optimization in microbiome research.
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Microbiome and Molecular Diagnostics Standards for Next-generation Sequencing-based Assays
One of the primary obstacles in standardizing metagenomics assays in microbiome research is the limited availability of reference materials and robust analytical tools. In this workshop, we discuss the development of mock microbial communities and explore their application as NGS standards in microbiome research.
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Models Providing High Biological Relevance and Predictability in Toxicological Assays
Developing cell-based assays can be problematic; the cells must be physiologically relevant for the assay to be predictive, yet sufficiently abundant to be included in the assay without introducing interexperimental variability. In this presentation, ATCC experts discussed the characteristics and utility of various respiratory, skin, and kidney models in toxicological assays.
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Next-Generation Cancer Models from the Human Cancer Models Initiative
In this presentation, Dr. Clinton provided an overview of the Human Cancer Models Initiative (HCMI) and the technologies driving the development of next-generation models.
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Responding to Public Health Threats through Global Biological Resource Programs
In this presentation, Dr. Riojas will briefly describe who ATCC and BEI Resources are and will detail our responses to recent infectious disease threats.
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The ATCC Genome Portal: Authenticity and Traceability for Microbial Genomes
This presentation highlights the importance of the authenticity and traceability of genomic data and details ATCC's approach to whole-genome sequencing, assembly, and genome annotation for producing high-quality, authenticated reference genomes.
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The Untapped Potential of ATCC's Mycology Collection
In this presentation, Dr. Knight-Connoni will discuss the diversity of the ATCC mycology collection and the application of these strains in bioremediation.
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The Value of Biological and Molecular Standards in Assay Development
This presentation examines the use of ATCC materials in molecular-based assays for cancer detection and analysis and assay development for infectious diseases.
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TransfeX: Superior Gene Expression for Hard-to-transfect Cell Types
ATCC offers a superior lipid-based transfection reagent (TransfeX) that can be used to transfect difficult cell types, like primary and stem cells, and uncomplicated continuous cell lines. In this presentation, we show how TransfeX provides higher transfection efficiency and lower cytotoxicity than other commercially available transfection reagents.
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