White Papers

Read the white paper to learn how ATCC Cell Line Land can help researchers confidently contribute to the advancement of scientific knowledge in a reliable and transparent manner, ensuring the integrity of their data and findings.

Read this white paper to explore how prokaryotes are authenticated at ATCC.

Read this white paper to learn more about multidrug resistance and how alternative treatment such as bacteriophage therapy may offer a promising mechanism for the eradication of infection.

In this white paper we review the current models and techniques used in cancer research and discuss the use of bioluminescence imaging for the precise histological measurement of tumors.

Discover more about the challenges associated with evaluating the analytical performance of a molecular assay and find guidance on selecting the ideal reference materials.

ATCC has been steadily expanding an array of CRISPR/Cas9 genome-editing capabilities and leveraging its extensive library of human cell lines for the development of custom-engineered, biomarker-specific human cancer models.

This white paper examines how the next generation of advanced cancer models are vital tools for furthering our understanding drug-resistance mechanisms and will help lead to faster development cycles and lower failure rates for both anticancer drug development and evaluation of combination therapy strategies.

Read this white paper to learn how molecular-based rapid microbiological methods provide contemporary technologies used to quickly and sensitively detect, enumerate, and identify microorganisms.

In this white paper, we review several predominant factors affecting reproducibility in life science research and outline efforts aimed at improving the situation.

Here, we will discuss the importance of choosing the appropriate external controls, and will provide information on how to select the appropriate cultures and nucleic acids for your tests.

In this white paper, we will discuss the importance of determining the detection limit in establishing analytical sensitivity, and will provide information on how to establish this parameter when evaluating your experimental design.

In this white paper, we discuss the importance of inclusivity/exclusivity testing, and will provide information on how to establish these parameters when evaluating your experimental design.

To ensure product safety, pharmaceutical companies must be versed in the important role of microbiological testing in product research and development, process validation, manufacturing, and quality control. Read this white paper to learn how ATCC supports the maintenance of product integrity, reputation, and safety by providing top-quality, fully characterized strains in a ready-to-use, familiar format.

In this article, we will discuss the effects of mycoplasma contamination, how this form of adulteration can affect cell-based drug development, and several quality control techniques and related products that can be used in the detection of mycoplasma contamination.

In this white paper, we discuss the importance of capsular polysaccharides in Streptococcus pneumoniae infection and describe the use of purified serotype-specific polysaccharides in the development and evaluation of pneumococcal vaccines, the verification of novel immunoassays, and tracking bacterial disease epidemiology.

In this white paper, we highlight the reporters commonly used in microbiological research and provide detail on the various applications of reporter-labeled strains.

Read this white paper for an overview of the relationship between the evolving practices of modern biorepositories and the current trends in pharmaceutical R&D.

In this white paper, we discuss the co-circulation and potential co-infection of the mosquito-borne Dengue (DENV), Chikungunya (CHIKV), and Zika (ZIKV) viruses; the challenges associated with the identification and discernment of these viruses; and the need for authenticated control materials for the validation of in vitro diagnostic tools.

The human microbiome changes over time with respect to lifestyle, the environment, and exposure to disease. This individual biology is a powerful tool for personalized healthcare and precision medicine.

In this white paper, we discuss how vaccine manufacturers can improve tuberculosis vaccine performance by utilizing a single, consensus biological reference standard that demonstrates high levels of protection when used in vaccine development.

In this white paper, we discuss the growing threat of antimicrobial resistance, novel therapeutic approaches, and the importance of antimicrobial-resistant reference strains in reducing the emergence and spread of multidrug-resistant infections.