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Cells contain SV40 sequences
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Note: These cells are cultured on vessels coated with 0.1% Gelatin (ATCC® No. PCS-999-027). Use 1.0 mL of gelatin per 10 cm2 surface area. Incubate at 37.0°C for ≥ 45 minutes. Aspirate gelatin just prior to adding cells to vessel(s).
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Wassmer S, et al. TGF-B1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. J. Immunol. 176: 1180-1184, 2006. PubMed: 16394007
Claessens A, et al. A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells. Proc. Natl. Acad. Sci. USA 109(26): E1772-E1781, 2012. PubMed: 22619330