• Careers
  • Support

Cell Models

Blue and purple ecad488 organoid cell models.

Advanced cell models boost your R&D

Scientists rely on a wide array of cells as experimental models for research

In vitro human cell line models have been widely used for applications such as toxicology, immunology, and cancer pharmacogenomic studies to predict therapeutic efficacy and to identify novel mechanisms associated with variation in drug response. ATCC advanced cell models such as luciferase-labeled cells, isogenic cells, neural progenitor cells, solute transporter carrier cells, and next-generation cell models will ensure your research results are reproducible and verifiable.

Cell models

A bright-green, fluorescent, EGFR stain sphere with a black background.

Isogenic Cells

Clinically relevant cell models are critical for studies of molecular and cellular mechanisms of tumors, as well as for drug screening for cancer. Using genome editing tools such as CRISPR/Cas9, ATCC has created isogenic cell lines with mutants of key oncogenes, which are ideal for identifying novel treatment regimens.

Get More Info
Closeup of a black and red firefly showing his light while standing on a green leaf.

Luciferase-labeled Cells

Luciferase-labeled cell lines bridge the gap between in vitro and in vivo research for biological mechanism studies and drug development. This advanced model provides a highly sensitive means to measure biological processes in cell-based assays and to assess drug efficacy in live animal models through bioluminescence imaging.

Find Out More


HCMI cell models

We are continually adding 2-D and 3-D patient-derived cancer models to our portfolio. These next-generation models include both common as well as rare and understudied examples of cancer from numerous tissues.

Explore the collection

Immuno-oncology models

Explore our checkpoint luciferase reporter cells, CAR-T target luciferase reporter cells, THP-1 reporter cells, and primary immune cells that support the development of immuno-oncology therapies.

Explore now
Green and blue dopaminergic Diff Tuj1 DAPI cells.

Neural Progenitor Cells

Neural Progenitor Cell (NPC) solutions from ATCC are potent models of normal and disease neurobiology and important tools for investigating neural development, degeneration and regeneration, neurogenetics, neural excitability, nervous system disorders, neurotransmitters, neurotoxicity, and drug screening.

More NPC Info
Blue and pink hTER renal proximal tubular epithelial cells.

Solute Transporter Carrier Cells

There is growing demand for in vitro kidney transporter models with normal human renal function. By using well-characterized hTERT-immortalized RPTEC's that stably overexpress the OAT1, OCT2, or OAT3 gene, ATCC created kidney cell models that provide renal tissue-relevant results and predictability for clinical trials.

Find Out More

Cell Models

Refine by