iPSC-derived Monocytes; DYS0100
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Human iPSC-derived Monocytes enables researchers to carry out application which are done using primary CD14+ monocytes. These cells can be used for differentiating into functionally active macrophages and dendritic cells. Additionally these cells can be used for MAT assay, drug development, toxicity screening, and cancer immunology experiments. There is an availability of large number of cell vials from a single donor.
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Panicker LM, et al. Gaucher iPSC derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development. Stem Cells 32(9): 2338-49, 2014. PubMed: 24801745
Spiller KL, et al. Differential gene expression in human, murine and cell line-derived macrophages upon polarization. Exp Cell Res 347(1): 1-13, 2015. PubMed: 26500109