Why leading drug, vaccine, and cell therapy developers choose ATCC PBMCs
ATCC PBMCs provide a physiologically relevant mix of immune cells—ideal for modeling immune responses, screening immunomodulatory compounds, and evaluating off-target effects in preclinical studies. With high-fidelity performance, consistent quality, and assay-ready functionality, our PBMCs help innovators push boundaries, accelerate discovery, and build confidence from bench to clinic.
Features and benefits Applications of PBMCs Explore our PBMC collection Contact us for assistance choosing PBMCs
Key features for advanced therapeutics
- Heterogeneous cell composition: Includes T cells, B cells, NK cells, and monocytes—ideal for immunogenicity and mechanism-of-action studies.
- Post-thaw viability: Maintains high recovery and function after thawing, critical for time-sensitive workflows.
- Assay-ready: Validated for use in ELISA, qPCR, flow cytometry, cytotoxicity, and mixed lymphocyte reactions (MLRs).
- Donor profiles: Provided on CoA to match trial cohorts or target populations.
- Ethically sourced: Fully traceable and compliant with ethical and legal standards.
- Comprehensive testing:
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Serological for Syphilis
Unexpected red cell antibody
Hepatitis B core antibody (Anti-HBc EIA)
Hepatitis B surface antigen (HBsAg EIA)
Hepatitis C virus antibody (Anti-HCV EIA)
Human immunodeficiency virus antibody (HIV 1/2 plus O)
Human T-lymphotropic virus antibody (HTLV-I/II)
HIV-1/HCV/HBV nucleic acid
West Nile virus nucleic acid
Trypanosoma cruzi antibody (Chagas Disease)
PBMC application areas
PBMCs are transforming biomedical research. From decoding immune responses to advancing cancer therapies like CAR-T, PBMCs are central to innovation in immunology, oncology, and infectious disease. They power vaccine development, illuminate autoimmune mechanisms, and enable personalized medicine through genomic and biomarker analysis. As sources for key immune cells and even reprogrammable stem cells, PBMCs are driving breakthroughs in cellular therapy, drug discovery, and regenerative medicine—making them indispensable tools in shaping the future of health.
Immunological research
Immune response studies
T cell function assays
B cell activation and antibody production
Cancer research and immunotherapy
Tumor infiltrating lymphocyte studies
CAR-T cell therapy development
Cancer immunosurveillance
Cell therapy & regenerative medicine
T cell therapies
Monocyte-derived dendritic cells
Natural killer cell therapy
Vaccine development and testing
Vaccine efficacy evaluation
Immunogenicity studies
Infectious disease research
HIV research
Viral and bacterial infection studies
Autoimmune disease research
Autoimmune mechanisms
Cytokine profiling
Transplantation research
Graft-versus-host disease studies
Tolerance induction
Toxicology and drug screening
Immunotoxicity testing
Cytotoxicity assays
Personalized medicine
Biomarker discovery
Genomic and transcriptomic analysis
See how we've used PBMCs in our research
Rapid NK Cell Cytotoxicity Assay
Discover a simple, non-radioactive alternative to the traditional 51Chromium release assay for quickly and reproducibly quantifying natural killer cell activity.
In Vitro Differentiation of Macrophages and Dendritic Cells
Explore the differentiation potential of cryopreserved primary human CD14+ monocytes toward macrophage and dendritic cell lineages.
