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ISSX 2026

Hilton San Francisco Union Square, San Francisco, California

October 11, 2026 - October 14, 2026

Meet ATCC at ISSX 2026 booth #311

Building more predictive models for therapeutic discovery

The ISSX 27th North American Meeting brings together scientists advancing drug metabolism, pharmacokinetics, and translational research through new therapeutic modalities and emerging technologies. ATCC supports the development of more predictive in vitro models and testing strategies with authenticated biological materials, physiologically relevant cell systems, and associated omics data. Together, these resources help researchers generate actionable insights that improve confidence in safety assessment, toxicity testing, and drug development decision-making.

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Join Our Presentation

Advancing Human-Relevant Drug Discovery Through the Integration of Primary Cells, Patient-Derived Organoids, and Microphysiological Systems

Speaker: Abhay Andar, PhD, Lead Scientist, ATCC | Date: October, 12, 2026 | Time: 2:10 PM – 2:25 PM

Discover how integrating primary human cells, patient-derived organoids, and microphysiological systems can create more predictive, human-relevant models that accelerate drug discovery, improve translational research, and support the adoption of New Approach Methodologies (NAMs).

Check Out Our Poster

Modeling MASLD with Primary Human Hepatocytes in a Physiologically Relevant Microfluidic Platform

Presenter: Changsuk Moon, PhD, Senior Scientist, ATCC | Date: October 13, 2026 | Time: 12:45 PM – 1:30 PM | Poster Number: P80

Learn how primary human hepatocytes can be used in a microfluidic microphysiological system to create a physiologically relevant metabolic dysfunction-associated steatotic liver disease (MASLD) model that reproduces key disease features and supports translational toxicology and drug discovery research.

Meet our scientists

Headshot of Headshot of Abhay U. Andar, PhD

Abhay U. Andar, PhD

Lead Scientist, Microphysiological Systems, ATCC

Dr. Abhay U. Andar has over 13 years of experience in translational oncology, microfluidics, and advanced in vitro disease modeling. At ATCC, Dr. Andar leads the Human Cancer Model Initiative (HCMI) portfolio, which includes over 300 patient-derived cancer models spanning 28 indications. His research focuses on developing organoid systems to support therapeutic discovery and translational research in oncology. Dr. Andar earned his Ph.D. and M.Sc. in Biomedical Science and Engineering from the University of Glasgow, and a B.Sc. in Life Sciences from the University of Mumbai. He has authored numerous publications and patents in cancer research, microfluidics, and therapeutic manufacturing, with work featured in Nature Materials, Nature Biomedical Engineering, Lab on Chip, Cancer Research, and Biotechnology and Bioengineering. Dr. Andar’s innovations in Tumor-on-Chip platforms, organoid generation, and immune co-culture systems continue to shape the future of personalized medicine and drug discovery.

Changsuk Moon.png

Changsuk Moon, PhD

Senior Scientist, ATCC

Changsuk Moon, PhD, is a Senior Scientist at ATCC where she has been developing advanced 3-D in vitro models and microphysiological systems for translational and preclinical research since 2023. Before joining ATCC, she spent over eight years in Boston-area biotechnology and pharmaceutical companies, where she led programs in rare diseases, in vitro model development, assay development, drug screening, and mechanism-of-action studies. Her expertise includes organoids, organ-on-a-chip technologies, primary human cell models, and translational platforms that bridge preclinical research and clinical application. She is dedicated to advancing human-relevant models that improve drug development efficiency and predictive safety assessment.

Explore our featured portfolios

Scientist using pipette to fill well-plate

Primary human hepatocytes

Primary human hepatocytes are considered the gold standard for in vitro liver models due to their high predictive value in drug metabolism and toxicity studies. They can provide early insights into how a drug will behave in the human body, potentially reducing the risk of adverse effects in clinical trials. ATCC HepatoXcell™ hepatocytes are meticulously isolated and characterized to ensure the highest quality and performance for your drug development and toxicity testing needs.

Explore primary human hepatocytes
Illustration showing multiple three‑dimensional organoids suspended in a soft blue‑purple background. A large organoid in the foreground displays complex folded epithelial structures, lumen‑like cavities, and densely packed cellular layers in shades of purple, blue, and gold, while additional organoids appear at varying depths throughout the scene.

Organoids

During the drug discovery process, having access to models that recapitulate tumor properties is essential for predictive screening. ATCC provides patient-derived 3-D organoid models annotated with molecular and clinical data that represent a variety of healthy and cancerous tissues. These next-generation cancer models are capable of long-term expansion in culture while remaining phenotypically and genetically stable.

Explore patient-derived organoids

Explore our featured resources

Gloved hands of young modern scientist preparing all the necessary equipment before carrying out new clinical experiment Brochure

Primary Human Hepatocytes

Discover how HepatoXcell™ can support your predictive drug development and toxicity testing.

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Purple and green top mouse skin cancer cells. Culture guide

ATCC Animal Cell Culture Guide

This guide contains general technical information for working with animal cells in culture, including media, subculturing, cryopreservation, and contamination.

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3D Illustration Concept of Human Respiratory System Lungs Anatomy Application note

Comparing Toxicological Responses Between ALI-Incubated Primary Airway Epithelial Cells and Undifferentiated Counterparts

In this application note, we show that self-constructed airway models may serve as useful tools future airway toxicity research.

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White, green and blue kidney glomeruli. Application note

Genetically Modified Renal Proximal Tubule Epithelial Cells - A Physiologically Relevant Renal Solute Carrier Uptake Model for Drug Toxicity Studies

We created three different hTERT-immortalized human primary renal proximal tubule epithelial cells (RPTEC) that stably express the OAT1, OCT2, and OAT3 proteins. We then tested the ability of these cells to intracellularly convey known SLC protein substrates.

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Green and red kidney cells. Application note

hTERT-immortalized and Primary Keratinocytes Differentiate into Epidermal Structures in 3D Organotypic Culture

In this study, we confirmed that an immortalized keratinocyte cell line, Ker-CT, is able to differentiate into organotypic skin equivalents in a 3D culture model

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Green and blue NuLi lung epithelial small airway cells. Brochure

hTERT-immortalized Primary Cells

Enjoy the best of all worlds with human telomerase reverse transcriptase (hTERT)-immortalized Primary Cells from ATCC.

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Close-up of pipette of drops of clear red media falling into wells culture plate, ripples on the surface of the media. Brochure

Primary Cell Solutions

ATCC Primary Cell Solutions is a system of matched components designed to boost growth, maximize functionality, and maintain normal morphology for each primary cell type.

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85757796[3] Lymphoma cancer cell re-colored.jpg Brochure

Primary Human Immune Cells

ATCC primary immunology cells are able to support complex, physiologically relevant research projects, including toxicity screening, transplantation and graft rejection, inflammation and allergy, vaccine, drug development, and cancer immunology studies.

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Neural progenitor cell derived neurosphere Application note

Establishment of 3-D Neurosphere Culture from Human iPSC-Derived Neural Progenitor Cells

This report describes a straightforward and robust method of generating neurospheres from neural progenitor cells

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ThawReady™ Assay Ready Cells

Eliminate lengthy cell expansion protocols with ThawReady™ Assay Ready Cells. Go from frozen to data in one day!

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Laboratory scientist holding a culture vessel against a dark purple background, surrounded by illustrations and terms related to organoids, spheroids, organ‑on‑a‑chip models, cancer research, growth kinetics, and clinical relevance. Brochure

Human Cancer Models Initiative (HCMI)

ATCC offers a growing collection of models generated by the HCMI, which will include both common as well as rare and understudied examples of cancer from numerous tissues

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Female scientist conducting an experiment lab. Application note

RNA-seq Reveals Comprehensive Gene Expression Landscape in Primary Human Hepatocytes

This application note shows how RNA-seq reveals key gene expression differences in primary human hepatocytes from different donors.

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