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Preclinical Toxicology PK Metabolism

Explore our resources below to discover how neurological and renal cell models can support your metabolic stability, metabolite identification, and drug-drug interaction assays.

Pharmacology, Exploratory, Toxicology

Do you need a model that reflects true physiology? Get started with differentiated iPSCs and primary and hTERT-immortalized primary cells.

Modeling, Screening, Characterizing

Are you in the preliminary stages of toxicity testing? Start on the path to success with our complete solution of cell lines, media, and reagents.

Cell Lines for Toxicology

Authenticated ATCC cells ensure your toxicology results are accurate. Explore our complete set of solutions today!

Functional models for exploring the ADME of a new chemical entity

Testing for absorption, distribution, metabolism, and excretion (ADME) is crucial to moving your product to market. Get closer results to those observed in vivo and rule out possible toxicities faster by using our entire ADME portfolio, featuring our primary human hepatocytes, neural progenitor cells, and hTERT-immortalized renal transport protein-expressing kidney cells. ATCC is here to support your metabolic stability, metabolite identification, and drug-drug interaction assays with our neurological and renal cell models.

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Human iPSC-derived Neural Progenitor Cells

Explore the differentiation of neural progenitor cells into multiple neuron types and the use of these cells in toxicological studies.

Read the Application Note

Renal Solute Carrier Uptake Models

Learn more about the creation and application of hTERT-immortalized human primary RPTECs that stably express the OAT1, OCT2, or OAT3 proteins.

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Watch our webinar to learn about the use of neural progenitor cells in toxicology studies