iPSC-derived CD34+ Cells, BXS0117
Generally ships within 1-3 business days
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ATCC highly recommends that appropriate personal protective equipment is always used when handling vials. For cultures that require storage in liquid nitrogen, it is important to note that some vials may leak when submersed in liquid nitrogen and will slowly fill with liquid nitrogen. Upon thawing, the conversion of the liquid nitrogen back to its gas phase may result in the vial exploding or blowing off its cap with dangerous force creating flying debris. Unless necessary, ATCC recommends that these cultures be stored in the vapor phase of liquid nitrogen rather than submersed in liquid nitrogen.
Biopharma: Cancer immunology, drug development, toxicity screening, and blood lineage differentiation studies.
Human iPSC-derived CD34+ can be used for drug development, toxicity screening, and cancer immunology experiments. There is reduced lot-to-lot variability in this cell line as they are all derived from the parental iPSC line (ATCC ACS-1031) .
The product is provided 'AS IS' and the viability of ATCC® products is warranted for 30 days from the date of shipment, provided that the customer has stored and handled the product according to the information included on the product information sheet, website, and Certificate of Analysis. For living cultures, ATCC lists the media formulation and reagents that have been found to be effective for the product. While other unspecified media and reagents may also produce satisfactory results, a change in the ATCC and/or depositor-recommended protocols may affect the recovery, growth, and/or function of the product. If an alternative medium formulation or reagent is used, the ATCC warranty for viability is no longer valid. Except as expressly set forth herein, no other warranties of any kind are provided, express or implied, including, but not limited to, any implied warranties of merchantability, fitness for a particular purpose, manufacture according to cGMP standards, typicality, safety, accuracy, and/or noninfringement.
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Please see the material transfer agreement (MTA) for further details regarding the use of this product. The MTA is available at www.atcc.org.
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This material is subject to the following restrictions in addition to those outlined in the ATCC Material Transfer Agreement:
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Espinoza JL, et al. Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack. Blood Adv 2(4): 390-400, 2018. PubMed: 30201698
Tan YT, et al. Respecifying human iPSC-derived blood cells to highly engraftable hematopoietic stem and progenitor cells with a single factor PNAS 9(115): 2180-2185, 2018. PubMed: 29386396