Primary Epidermal Melanocytes; Normal, Human, Neonatal (HEMn)
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All tissues used for isolation are obtained under informed consent and conform to HIPAA regulations to protect the privacy of the donor’s Personally Identifiable Information. It is best to use caution when handling any human cells. We recommend that all human cells be accorded the same level of biosafety consideration as cells known to carry Human immunodeficiency virus (HIV) and other bloodborne pathogens. With infectious virus assays or viral antigen assays, even a negative test result may not exclude the possibility of the existence of a latent viral genome or infectious viral particles below the lower limit of detection of that assay.
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Lobos-Gonzales L, et al. Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models. Melanoma Res 24(2):108-119, 2014. PubMed: 24500501
Tian, F et al. miR-33a Is Downregulated in Melanoma Cells and Modulates Cell Proliferation by Targeting Pctaire1. Oncol Lett 4(11):2741-46, 2016. PubMed: 27073545
Gutteridge RE, et al. Targeted Knockdown of Polo-Like Kinase 1 Alters Metabolic Regulation in Melanoma. Cancer Lett 394:13-21, 2017. PubMed: 28235541
Oehler B, et al. TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde. Naunyn-Schmiedebergs Arch Pharmacol 385(6):555-563, 2012. PubMed: 22426997
Yang B, et al. Hyperoside Protects Human Primary Melanocytes against H2O2-Induced Oxidative Damage. Mol Med Rep 6(13):4613-9, 2016. PubMed: 27082158