A Foundational Resource for Advancing the Next 100 Years of Discovery

As we look ahead to the next century of discovery, the need for gold-standard science and traceability has never been greater. ATCC is committed to advancing next-generation biological standards and models and generating authenticated datasets alongside our authenticated microbial strains and cell lines. These innovations will empower researchers to explore biology with unprecedented precision, opening new pathways for medical advances, biomanufacturing, AI-driven in silico discovery, and more.

Through global partnerships with leading research institutions and consortia, ATCC ensures that scientists worldwide have access to standardized, high-quality resources, fostering collaborative innovation that transcends borders and drives breakthroughs in every region. Domestically, we have partnered with the federal government for over 60 years, contributing to national priorities in health, biosecurity, and domestic biomanufacturing by providing authenticated, high-quality materials fully traceable to validated data.

Alternatives to Animal Testing

The scientific landscape is undergoing a profound transformation as the FDA and NIH champion frameworks that prioritize human-based research technologies over traditional animal testing. The shift toward New Approach Methodologies (NAMs)—including human cell–based assays, organoid toxicity testing, and AI-powered models—is redefining how safety and efficacy are established in preclinical studies.

ATCC is at the forefront of this transition, equipping researchers with the authenticated cells, organoids, and MPS-qualified biologicals paired with harmonized protocols needed to replace animal models with human-relevant systems. Authenticated cells are critical building blocks for 3-D models and ATCC ensures these resources are rigorously qualified and validated to deliver reliability for complex experimental platforms.

Through our collaboration with The Human Cancer Models Initiative (HCMI), ATCC provides nearly 350 human-derived cell lines and organoids, spanning 28 tissue types and diverse demographics, offering direct alternatives to animal models. These authenticated materials minimize variability, and advanced 3-D systems replicate human physiology with unprecedented accuracy. By enabling researchers to adopt NAMs, ATCC supports the global scientific community in reducing reliance on animal testing, accelerating the transition to next-generation models that pair authenticated biomaterials with harmonized protocols and curated genomic data.

Unlocking Discoveries through Digital Biology

In the era of digital biology, data accuracy defines the future of discovery. ATCC empowers researchers by delivering authenticated biomaterials paired with high-quality, curated omics data, providing a foundation for reliable AI predictions and precision insights that accelerate scientific breakthroughs. By creating traceable, high-quality datasets matched to our physical biological materials, ATCC is enabling scientists to perform data-driven research that can help identify gene targets, predict drug responses, simulate cell behavior, and more. ATCC is leading the way in predictive modeling by offering the unique combination of physical source materials with the corresponding ‘omics data.

At the heart of this transformation is the ATCC Genome Portal, a rapidly expanding platform that provides next-generation sequencing data from rigorously authenticated biomaterials in the ATCC collection. The ATCC Genome Portal enables researchers to perform confident bioinformatics analyses, uncover meaningful connections, and drive reproducible science forward.

Ultimately, the reliability of biological insights depends entirely on the quality of the data, and most importantly, the source materials. With ATCC’s trusted resources, discovery will advance in ways unimaginable a century ago.

Celebrating our Incredible Employees

Our work wouldn’t be possible without our incredibly talented team of scientists and professionals driven by our common goal of advancing innovation and discovery. Our employees have authored numerous publications and regularly share their knowledge and expertise through scientific presentations, posters, and industry article contributions. We encourage our team members to learn, grow, and connect through career development opportunities, a rewards and recognition program, a comprehensive benefits package, and fun companywide events.

ATCC is proud to be recognized as a top workplace once again in 2025, earning multiple awards that reflect our commitment to collaboration, integrity, and purpose. We were named a BioSpace Best Place to Work, achieved Great Place To Work Certified™ status for the third consecutive year based on employee feedback, and honored as one of Prince William Living’s Best Places to Work. These accolades underscore our dedication to fostering an environment where employees thrive while advancing life science research worldwide.

Looking Ahead

Our journey from a small culture collection to a global leader in biological materials, data, and standards reflects a century of progress. We remain dedicated to empowering researchers globally with trusted resources, advanced models, and reference-grade data—united in our mission to support impactful innovation.

Thank you for being part of this incredible journey. Here’s to a future where discovery knows no limits.

Did you know?

ATCC is pioneering cell components for organ-on-chip microphysiological systems and advancing cryobiology to ensure long-term stability of complex human cell models.