Toxicity Testing Takes Time

Why it's important

You can avoid late stage drug development failure if you start the preclinical stage with reliable and authenticated standards and model organisms. Quality cells, media, and reagents allow you to test using in vitro models to predict in vivo outcomes. Better to ‘fail early’ than to spend years, and hundreds of millions of dollars only to fail in clinical trials!

How we can help

ATCC authenticated cell models will ensure your research results are credible and reproducible. We share our research with you in several in-person and online events.

This week, on October 6 we broadcast a webinar entitled, Evaluating the Differentiation Potential of Primary Airway Cells in 3-D Models. In this webinar we show techniques and procedures that can help you reliably generate 3-D airway models with consistent full epithelial differentiation. On November 2, our webinar Does Differentiation Matter? Comparing the Toxicological Response Between Airway Epithelial Models further explains how advanced 3-D airway models can be used to assess short- and long-term exposure to chemicals and may provide more predictive information for use in pharmaceutical development, toxicity testing, and basic research.

From November 13 - 16, we will attend the American College of Toxicology (ACT) 2022 Annual Meeting in Denver, Colorado and present a poster showcasing our portfolio of products that support toxicology and toxicity testing.

We also featured several webinars in early 2022 that discuss other toxicology research and development at ATCC and share our results with you.

In the webinar, Kidney SLC Transporter Cells – Reliable Tools for Assessing Renal Solute Passage and Drug Toxicity, ATCC presents physiologically relevant transporter cell models created using hTERT-immortalized primary renal proximal tubule epithelial cells (RPTEC) that stably overexpress the OAT1, OCT2, or OAT3 gene. Our experts share the data indicating that these cell lines provide tissue-relevant results, improved consistency over time, and predictability for clinical trials. Learn how these models can save you time and can support your toxicological studies.

hTERT-immortalized primary melanocytes provide tissue-relevant results and reproducibility for any cell-based assay. These melanocytes have been tested and validated for longevity and to maintain primary cell features, such as melaninogenesis. Immortalized Melanocytes can be used for performing studies of the complex process of skin pigmentation, high throughput screening, environmental/cosmetic toxicology, and basic research into cell metabolism. Watch the webinar, hTERT-immortalized Melanocytes – Advanced Models for Your Dermal Toxicity Studies to learn how they can be used in your research,

Explore All Webinars