Next-generation Sequencing (NGS) Standards Innovation Challenge 2022 Winner
We are excited to announce that Dr. Girish Neelakanta from the University of Tennessee submitted the winning entry in ATCC's recent innovation challenge. In this challenge, we called upon innovators throughout the scientific community to submit a proposal of how they are using ATCC NGS Standards in new, interesting, or daring applications.
Dr. Neelakanta's research
Ticks are known to transmit a variety of pathogens to humans and other vertebrate hosts. To obtain a successful blood meal, ticks must secrete saliva during feeding to modulate the host immune response to suppress clotting, antibody production, complement activation, and cytokine production. This modulation not only facilitates feeding but also enables the transmission of pathogens from the tick to the host. While skin immunity is known to play a role in the tolerance of tick-borne pathogens, the role of the skin microbiome in immunomodulation during tick feeding is not well understood. In this study, the team seeks to characterize whether tick feeding and transmission of the pathogen Anaplasma phagocytophilum modulates the host skin microbiome. The ATCC Skin Microbiome Genomic Mix (ATCC MSA-1005) will be used as a control in quantitative real-time PCR assays throughout the study. The findings from this study will provide valuable insights into vector-borne disease and vector biology.
Did you know?
Vector-borne diseases annually contribute to more than 700,000 deaths globally.
Anne McCormack, BA
Digital Marketing Specialist, ATCC
Anne is a Digital Marketing Specialist at ATCC. She is editor of ATCC's Credible Conversations blog. She works collaboratively with scientists at ATCC to share innovation and lively topics of interest with the ATCC audience. Anne has over 20 years experience writing and editing science articles for print publications such as New Technology Week, Manufacturing and Technology News, and for websites including AOL and the National Geographic Society.
Cara Wilder, PhD, ELS
Senior Scientific Writer, ATCC
Dr. Wilder is a Senior Scientific Writer at ATCC. She has a PhD in Microbiology with background experience working with several pathogenic bacterial species in both in vitro and in vivo environments. Dr. Wilder is the author of numerous publications on varying topics of scientific relevance, including quality control, microbial contamination, assay development, proficiency testing, and multidrug resistance.
Find more resources for tick-borne disease research
Vector-borne Diseases
To aid in vector-borne disease research, ATCC has compiled a collection of microbial species known to be transmitted by arthropod vectors.
More
Webinar
Tick-borne Diseases: Developing Molecular Approaches to Detect Babesiosis
Tick-borne diseases (TBD) among humans are on the rise in the United States as urbanization along previously unpopulated areas continues. In this webinar, we will provide an overview of TBD epidemiology, the current status of diagnostic methods, and resources available from ATCC that advance TBD research priorities.
More
Microbiome Research
ATCC's NGS standards for microbiome research are completely manufactured from high-quality, authenticated, fully sequenced ATCC cultures that are characterized by polyphasic testing. These standards support a broad array of applications ranging from method optimization to data interpretation, and they serve as superior controls for microbial community testing and assay development on any platform.
MoreExplore additional applications for NGS Standards
Application note
Development and Evaluation of Whole Cell- and Genomic DNA-based NGS Standards
In this study, we demonstrate that ATCC NGS Standards combined with the One Codex data analysis module provide a comprehensive solution for standardizing data from a wide range of sources, and generating consensus among microbiome applications and analyses.
More
Application note
Development and Evaluation of Next-generation Sequencing Standards for Virome Research
In this study, we describe the development and quality control of the ATCC virome standards and present application data demonstrating their use throughout the different stages of a typical virome analysis workflow.
More
Application note
Use of Recombinant Bacteria with Unique Tags as Spike-in Controls for Microbiome Studies
In this application note, we describe the construction and application of ATCC Spike-in Standards as a tool for quantitative metagenomic analysis.
MoreWe support your innovative research
Interested in joining one of our upcoming innovation challenges?
Fill out the form to be notified when our next challenge begins. We can't wait to see your innovative proposal!
Your form was successfully submitted
