Innovation Challenge 2022 - NGS Standards

Purple, fragmented DNA double helix strand on a black background.

Innovation Challenge 2022: ATCC NGS Standards

Innovation Challenge 2022 - Winners

We are here to support critical scientific discoveries

Thank you to everyone who participated in the recent ATCC Innovation Challenge! In this challenge, we called upon innovators throughout the scientific community to submit a proposal of how they are using ATCC NGS Standards in new, interesting, or daring applications.

After receiving numerous submissions, we are pleased to announce the winner of the challenge below. We're proud to be a part of this incredible research and we look forward to this innovative idea coming to fruition.

Congratulations to our winner

Dr. Girish Neelakanta, University of Tennessee
Ticks are known to transmit a variety of pathogens to humans and other vertebrate hosts. To obtain a successful blood meal, ticks must secrete saliva during feeding to modulate the host immune response to suppress clotting, antibody production, complement activation, and cytokine production. This modulation not only facilitates feeding but also enables the transmission of pathogens from the tick to the host. While skin immunity is known to play a role in the tolerance of tick-borne pathogens, the role of the skin microbiome in immunomodulation during tick feeding is not well understood. In this study, the team seeks to characterize whether tick feeding and transmission of the pathogen Anaplasma phagocytophilum modulates the host skin microbiome. The ATCC Skin Microbiome Genomic Mix (ATCC MSA-1005) will be used as a control in quantitative real-time PCR assays throughout the study. The findings from this study will provide valuable insights into vector-borne disease and vector biology.

Products that applied in this challenge

Green floating balls of Staphylococcus epidermidis bacteria tangled with purple tendrils.

ABRF-MGRG 6 Strain Even Mix Genomic Material

This mock microbial community comprises an even mixture of genomic DNA from fully sequenced, characterized, and authenticated bacterial and archaeal species. This product is ideal for assay development and environmental analyses.

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A cluster of green, rod-shaped clostridium bacteria.

ABRF-MGRG 10 Strain Even Mix Genomic Material

This product comprises genomic DNA from fully sequenced, characterized, and authenticated bacterial and archaeal species observed in various environments, including soil, freshwater, seawater, feces, and high salinity ecosystems.

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Blueish purple rods of Escherichia coli bacteria.

ABRF-MGRG 10 Strain Staggered Mix Genomic Material

This product comprises a staggered mix of genomic DNA from fully sequenced, characterized, and authenticated bacterial and archaeal species observed in various environments.

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10 Strain Even Mix Genomic Material

Mock microbial community comprising an mixture of 10 genomic DNA preparations.

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10 Strain Even Mix Whole Cell Material

An even mixture of 10 strains that were selected based on relevant phenotypic and genotypic attributes.

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DNA helix strands in yellow, orange, purple, and green.

20 Strain Even Mix Genomic Material

Even mixture of 20 genomic DNAs prepared from fully sequenced, characterized, and authenticated strains.

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20 Strain Staggered Mix Genomic Material

Mock microbial community comprising a staggered mixture of 20 genomic DNA preparations.

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10 Strain Staggered Mix Genomic Material

Genomic DNA prepared from fully sequenced, characterized, and authenticated ATCC Genuine Cultures.

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Spike-in Whole Cell Mix

This product comprises an even mixture of 3 tagged strains and can be used as a true run control from sample storage all the way through data analysis.

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Spike-in Genomic DNA Mix

This standard comprises an even mixture of tagged genomic DNA and can be used to evaluate extraction methods and compare and validate sequencing platforms.

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Small, bright pink flat, paddle-shaped Mycoplasma genitalium bacteria.

Vaginal Microbiome Genomic Mix

This product comprises an even mixture of genomic DNA prepared from fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical vaginal microbial communities.

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Several floating strings of purple drug-resistant Streptococcus pneumoniae spheres.

Vaginal Microbiome Whole Cell Mix

This product is prepared as an even mixture of whole cells and comprises fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical vaginal microbial communities.

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Round, yellow balls of methicillin resistant staphylococcus aureaus.

Skin Microbiome Genomic Mix

Explore the effects of dysbiosis on human health with the Skin Microbiome Genomic Mix. This product comprises an even mixture of genomic DNA prepared from fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical skin microbial communities.

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Skin Microbiome Whole Cell Mix

An ideal standard for investigating the microbiome of the epidermis. The Skin Microbiome Whole Cell Mix is an even mixture of whole cells and comprises fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical skin microbial communities.

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Fluorescent pink, rod-shaped Escherichia coli bacteria.

Gut Microbiome Genomic Mix

This product comprises an even mixture of genomic DNA prepared from fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical gut microbial communities.

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Tiny beads of pink and purple bacteria in MacConkey growth medium.

Oral Microbiome Genomic Mix

This product comprises an even mixture of genomic DNA prepared from fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical oral microbial communities.

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Oral Microbiome Whole Cell Mix

This product is prepared as an even mixture of whole cells and comprises fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical oral microbial communities.

Get the whole cell mix

Yellow, connecting rods of Klebsiella pneumoniae.

Metagenomic Control Material for Pathogen Detection

This product comprises genomic DNA prepared from fully sequenced, characterized, and authenticated ATCC Genuine Cultures, and was quantitated using Droplet Digital™ PCR to improve precision in relative abundance among strains within the community.

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Virome Nucleic Acid Mix

This product comprises an even mixture of nucleic acids prepared from fully sequenced, characterized, and authenticated viral strains selected on the basis of genomic size, DNA/RNA genome, envelope/non-envelope, and other special features.

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Round, iridescent, green-blue H1N1 (swine flu) virus with protrusions.

Virome Virus Mix

This virome standard is a mock microbial community that mimics mixed metagenomic samples. This product comprises an even mixture of fully sequenced, characterized, and authenticated viral strains.

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We support your innovative research

Scientist wearing surgical smock, cap, mask, and gloves, looking into microscope while using pipette.

Interested in joining one of our upcoming innovation challenges?

Fill out the form to be notified when our next challenge begins. We can’t wait to see your innovative proposal!

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Innovate with ATCC

ATCC is open to collaboration, partnership, and working together to better support the groundbreaking discoveries that fuel life sciences. Send us opportunities for ATCC to in-license your patented innovations, sponsor your research, and explore partnerships by emailing your contact information and a brief description of the opportunity.