Disclosure
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This material is cited in a US or other Patent and may not be used to
infringe the claims. Depending on the wishes of the Depositor, ATCC may be
required to inform the Patent Depositor of the party to which the material was
furnished. This material may not have been produced or characterized by ATCC.
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Chain of Custody
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ATCC <-- NRRL <-- Merck & Co., Inc. MA-4680
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Isolation
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Soil, Ito City, Shizuoka Pref., Japan
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References
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Burg RW, et al. Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation. Antimicrob. Agents Chemother. 15: 361-367, 1979. PubMed: 464561
Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983
Hafner EW, et al. Cultures for production of B avermectins. US Patent 5,565,359 dated Oct 15 1996
Ikeda H, et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21: 526-531, 2003. PubMed: 12692562
Kim SB, Goodfellow M. Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes. Int. J. Syst. Evol. Microbiol. 52: 2011-2014, 2002. PubMed: 12508861
Miller TW, et al. Avermectins, new family of potent anthelmintic agents: Isolation and chromatographic properties. Antimicrob. Agents Chemother. 15: 368-371, 1979. PubMed: 464562
Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983
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Cross References
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Nucleotide (GenBank) :
AY029771
Streptomyces avermitilis ribosomal protein S12 (rpsL) gene, complete cds.
Nucleotide (GenBank) :
BA000030
Streptomyces avermitilis MA-4680 DNA, complete genome.
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