ATCC’s Toxicology Portfolio: Tools for Every Stage of Your Preclinical Drug Development Workstream Webinar

Cell-based toxicity assays require large numbers of biologically relevant cells for predictive, large-scale experiments. Primary cells immortalized by human telomerase demonstrate the growth characteristics of continuous cell lines without losing their physiological attributes. In this webinar ATCC scientists discuss the characteristics and utility of various respiratory, skin, and kidney models in toxicological assays. Additionally, the speakers will present data that demonstrates that these modified primary cells are effective tools that provide tissue-relevant results and reproducibility for any cell-based assay, including toxicology assays.

Key Points

• hTERT-immortalized primary cells are comparable to primary cells regarding physiological relevance, but are able to avoid replicative senescence
• Using well-characterized hTERT-immortalized cells, ATCC has created credible cell models for toxicological studies on the kidney, skin, and airway
• Our data show that these modified primary cells are effective tools that provide tissue-relevant results and reproducibility for any cell-based assay, including toxicology assays