Recombinant Adeno-associated virus 8 (ATCC® VR-1816)

Product Format: frozen 0.125 mL

Permits and Restrictions

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Agent Recombinant Adeno-associated virus 8
Strain Recombinant Adeno-associated Virus 8 Reference Standard Stock (rAAV8-RSS)
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen 0.125 mL
Storage Conditions -80°C or colder
Comments For additional information on handling the Recombinant Adeno-associated Virus 8 Reference Standard Stock, view the AAVRSWG Handling Guide located on the ATCC website at www.atcc.org.
Growth Conditions For additional information on handling the Recombinant Adeno-associated Virus 8 Reference Standard Stock, view the AAVRSWG Handling Guide located on the ATCC website at www.atcc.org.
Name of Depositor Adeno-associated Virus Reference Standard Working Group (AAVRSWG)
References

Ayuso E, et al. Reference materials for the characterization of adeno-associated viral vectors. In: Cohen-haguenauer, O (ed). The Clinibook: clinical gene transfer state of the art. EDK: Paris: pp. 83-90, 2012.

Moullier P, Snyder RO. Recombinant adeno-associated viral vector reference standards. Methods Enzymol. 507: 297-311, 2012. PubMed: 22365780

Moullier P, Snyder, RO. International efforts for recombinant adeno-associated viral vector reference standards. Mol. Ther. 16:1185-1188, 2008.

Burger C. et al. Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Molecular Therapy : 10(2):302-17, 2004 PubMed: 15294177

Tessier J, et al. Characterization of adenovirus-induced inverted terminal repeat-independent amplification of integrated adeno-associated virus rep-cap sequences. J. Virol. 75(1):375-383, 2001. PubMed: 11119606

Lock M, et al. Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Hum. Gene Ther. 21(10): 1273-1285, 2010. PubMed: 20486768

Ayuso E, et al. High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency. Gene Ther. 17(4): 503-510, 2010. PubMed: 19956269

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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