Liver Cancer Panel (ATCC® TCP-1011)

Components
SNU-475, ATCC CRL-2236
C3A [HepG2/C3A, derivative of Hep G2] ATCC CRL-10741
SNU-449, ATCC CRL-2234
PLC/PRF/5, ATCC CRL-8024
SNU-387, ATCC CRL-2237
SK-HEP-1, ATCC HTB-52
SNU-423, ATCC CRL-2238
Applications
Biological understanding of top genetic alterations across tumor types
Validation and characterization of potential cancer driver genes
Functional profiling and molecular profiling of subtype-specific cancer cell lines
Testing small molecules or biologics for cancer drug development
Type Strain no
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Comments
A panel of 7 liver cancer cell lines with varying degrees of genetic complexity. They have genomic mutations in one or more of the following genes according to the Sanger COSMIC database: BRAF, CDKN2A, CTNNB1, NRAS, STK11, and TP53.
Product Format frozen
Storage Conditions LN vapor (less than -130°C) only