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Neurofibromatosis Cell Panel

30-5500K

The NTAP (Neurofibromatosis Therapeutic Acceleration Program) cell panel consists of 6 hTERT-immortalized wild type NF1 and neurofibroma-derived cell lines harboring NF1 mutations. These are highly genotypically characterized tools for research in drug discovery and therapeutics. With generous support from NTAP, the purchasers of these cells are eligible to receive up to 100% reimbursement from NTAP

Components

hTERT NF1 ipNF05.5 (mixed clones) (ATCC CRL-3387)

hTERT NF1 ipNF05.5 (ATCC CRL-3388)

hTERT NF1 ipNF95.6 (ATCC CRL-3389)

hTERT NF1 ipNF95.11b C (ATCC CRL-3390)

hTERT NF1 ipNF95.11c (ATCC CRL-3391)

hTERT NF1 ipn02.3λ (ATCC CRL-3392)

 

 

Product format
Frozen
Shipping information
6 vials
Storage conditions
Vapor phase of liquid nitrogen
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Price: $13,000.00 ea
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Documentation

ATCC determines the biosafety level of a material based on our risk assessment as guided by the current edition of Biosafety in Microbiological and Biomedical Laboratories (BMBL), U.S. Department of Health and Human Services. It is your responsibility to understand the hazards associated with the material per your organization’s policies and procedures as well as any other applicable regulations as enforced by your local or national agencies.

ATCC highly recommends that appropriate personal protective equipment is always used when handling vials. For cultures that require storage in liquid nitrogen, it is important to note that some vials may leak when submersed in liquid nitrogen and will slowly fill with liquid nitrogen. Upon thawing, the conversion of the liquid nitrogen back to its gas phase may result in the vial exploding or blowing off its cap with dangerous force creating flying debris. Unless necessary, ATCC recommends that these cultures be stored in the vapor phase of liquid nitrogen rather than submersed in liquid nitrogen.

Detailed product information

Characteristics

Comments

Through generous support from the Neurofibromatosis Therapeutic Acceleration Program (NTAP), purchasers of these cells are eligible to receive up to a 100% reimbursement from NTAP.  For additional information and to apply for reimbursement after a purchase, please contact NTAP at [email protected] or visit the NTAP Website.

 For study of Schwann cell biology, diseases and tumors. These cells are invaluable tools for dissecting the processes contributing to the formation of neurofibromas and possibly other diseases, and the development of disease models and therapeutics.

The collection contains “normal” (wild-type) NF1(+/+),  NF1(+/-) (heterozygous), and NF1(-/-) homozygous (neurofibroma derived) human Schwann cell lines.  (NOTE: Cell-lines generated under auspices of the lab of Dr. Peggy Wallace, University of Florida, with funding support by the Neurofibromatosis Therapeutic Acceleration Program (NTAP) at Johns Hopkins University)

Legal disclaimers

Intended use
This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use.
Warranty

The product is provided 'AS IS' and the viability of ATCC® products is warranted for 30 days from the date of shipment, provided that the customer has stored and handled the product according to the information included on the product information sheet, website, and Certificate of Analysis. For living cultures, ATCC lists the media formulation and reagents that have been found to be effective for the product. While other unspecified media and reagents may also produce satisfactory results, a change in the ATCC and/or depositor-recommended protocols may affect the recovery, growth, and/or function of the product. If an alternative medium formulation or reagent is used, the ATCC warranty for viability is no longer valid.  Except as expressly set forth herein, no other warranties of any kind are provided, express or implied, including, but not limited to, any implied warranties of merchantability, fitness for a particular purpose, manufacture according to cGMP standards, typicality, safety, accuracy, and/or noninfringement.

Disclaimers

This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use. Any proposed commercial use is prohibited without a license from ATCC.

While ATCC uses reasonable efforts to include accurate and up-to-date information on this product sheet, ATCC makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. ATCC does not warrant that such information has been confirmed to be accurate or complete and the customer bears the sole responsibility of confirming the accuracy and completeness of any such information.

This product is sent on the condition that the customer is responsible for and assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, and use of the ATCC product including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. As a condition of receiving the material, the customer agrees that any activity undertaken with the ATCC product and any progeny or modifications will be conducted in compliance with all applicable laws, regulations, and guidelines. This product is provided 'AS IS' with no representations or warranties whatsoever except as expressly set forth herein and in no event shall ATCC, its parents, subsidiaries, directors, officers, agents, employees, assigns, successors, and affiliates be liable for indirect, special, incidental, or consequential damages of any kind in connection with or arising out of the customer's use of the product. While reasonable effort is made to ensure authenticity and reliability of materials on deposit, ATCC is not liable for damages arising from the misidentification or misrepresentation of such materials.

Please see the material transfer agreement (MTA) for further details regarding the use of this product. The MTA is available at www.atcc.org.

Frequently Asked Questions

References

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