Human genomic DNA (C13589) (ATCC® CRL-2704D)

Organism: Homo sapiens, human  /  Tissue: Peripheral blood  / 

Product Format frozen 10 µg
Storage Conditions -20°C or colder in a manual defrost freezer. Avoid freeze-thawing.
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Quality Control Specifications
> 100 kb in size by agarose gel electrophoresis

No RNA detected in the agarose gel

A260/A280 > ratio 1.8

Tested and verified for PCR amplification and restriction digestion.
Basic Documentation

The line was established from mononuclear cells taken from a fragile-X premutation female with 31 and 59 CGG-triplet repeats in the fragile-X gene, FMR1. This allele size is the smallest undergoing expansion to a full mutation (greater than 200 repeats) in one transmission. This expansion to a full mutation with greater than 200 repeats occurs only on transmission through females. Fragile X is a common cause of inherited mental retardation and is caused by an expansion of a CGG repeat within the gene.