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Raccoonpox virus


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Product category
Product type
Animal virus
Poxviridae, Orthopoxvirus
Strain designation
Genome sequenced strain
Isolation source
Isolated by Y.F. Herman from respiratory tract of raccoon with no clinical symptoms.
Geographical isolation
United States; Maryland
Product format
Storage conditions
-70°C or colder
Mission Collection Item
This is a Mission Collection Item.


ATCC determines the biosafety level of a material based on our risk assessment as guided by the current edition of Biosafety in Microbiological and Biomedical Laboratories (BMBL), U.S. Department of Health and Human Services. It is your responsibility to understand the hazards associated with the material per your organization’s policies and procedures as well as any other applicable regulations as enforced by your local or national agencies.

ATCC highly recommends that appropriate personal protective equipment is always used when handling vials. For cultures that require storage in liquid nitrogen, it is important to note that some vials may leak when submersed in liquid nitrogen and will slowly fill with liquid nitrogen. Upon thawing, the conversion of the liquid nitrogen back to its gas phase may result in the vial exploding or blowing off its cap with dangerous force creating flying debris. Unless necessary, ATCC recommends that these cultures be stored in the vapor phase of liquid nitrogen rather than submersed in liquid nitrogen.

Detailed product information


Specific applications
The virus cross-reacts serologically with the Connaught strain of vaccinia virus.
Cross-reacts with Connaught strain on vaccinia virus.


The virus does not grow well on chorioallantoic membranes after 2 to 3 passages.
The virus cross-reacts serologically with the Connaught strain of vaccinia virus.
Raccoons inoculated with RPV show no apparent clinical symptoms; however, their sera demonstrate strong HAI reactions.
Does not grow well on CAM after 2-3 passages. Cross-reacts with Connaught strain on vaccinia virus. Raccoons inoculated with RPV show no apparent clinical symptoms; however, their sera demonstrate strong HAI reactions.
Mycoplasma contamination
Not detected

Handling information

Host Range: Vero cells (ATCC CCL-81); LLC-MK2 cells (ATCC CCL-7); CAM; suckling mouse
CPE; paralysis; plaque formation; pock lesions on chorioallantoic membrane; syncytia
3-4 days
Handling notes
Does not grow well on CAM after 2 to 3 passages.  Cross-reacts with Connaught strain on vaccinia virus.  Racoons inoculated with raccoon pox virus show no apparent clinical symptoms, however, their sera demonstrate strong HAI reactions.

Key abbreviations
Arch., archives
CAM, Chorioallantoic membrane
CPE, Cytopathic effect
EMEM, Eagle's Minimum Essential Medium
FBS, Fetal bovine serum
HAI, Hemagglutination inhibition
LLC-MK2, Rhesus monkey kidney cells
EMEM, Eagle's Minimum Essential Medium
mL, Milliliter
Pen, Penicillin
PFU, Plaque forming units
SM, Suckling mouse
Strep, Streptomycin
TC, Tissue culture
TCID[50], Median tissue culture infective dose
Vero, African green monkey kidney cells
Virol., Virology

Quality control specifications

Verification method
Whole-genome Sequencing


Deposited as
Raccoonpox virus, Orthopoxvirus
JH Nakano
Type of isolate
Year of origin

Legal disclaimers

Intended use
This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use.

The product is provided 'AS IS' and the viability of ATCC® products is warranted for 30 days from the date of shipment, provided that the customer has stored and handled the product according to the information included on the product information sheet, website, and Certificate of Analysis. For living cultures, ATCC lists the media formulation and reagents that have been found to be effective for the product. While other unspecified media and reagents may also produce satisfactory results, a change in the ATCC and/or depositor-recommended protocols may affect the recovery, growth, and/or function of the product. If an alternative medium formulation or reagent is used, the ATCC warranty for viability is no longer valid.  Except as expressly set forth herein, no other warranties of any kind are provided, express or implied, including, but not limited to, any implied warranties of merchantability, fitness for a particular purpose, manufacture according to cGMP standards, typicality, safety, accuracy, and/or noninfringement.


This product is intended for laboratory research use only. It is not intended for any animal or human therapeutic use, any human or animal consumption, or any diagnostic use. Any proposed commercial use is prohibited without a license from ATCC.

While ATCC uses reasonable efforts to include accurate and up-to-date information on this product sheet, ATCC makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. ATCC does not warrant that such information has been confirmed to be accurate or complete and the customer bears the sole responsibility of confirming the accuracy and completeness of any such information.

This product is sent on the condition that the customer is responsible for and assumes all risk and responsibility in connection with the receipt, handling, storage, disposal, and use of the ATCC product including without limitation taking all appropriate safety and handling precautions to minimize health or environmental risk. As a condition of receiving the material, the customer agrees that any activity undertaken with the ATCC product and any progeny or modifications will be conducted in compliance with all applicable laws, regulations, and guidelines. This product is provided 'AS IS' with no representations or warranties whatsoever except as expressly set forth herein and in no event shall ATCC, its parents, subsidiaries, directors, officers, agents, employees, assigns, successors, and affiliates be liable for indirect, special, incidental, or consequential damages of any kind in connection with or arising out of the customer's use of the product. While reasonable effort is made to ensure authenticity and reliability of materials on deposit, ATCC is not liable for damages arising from the misidentification or misrepresentation of such materials.

Please see the material transfer agreement (MTA) for further details regarding the use of this product. The MTA is available at

Permits & Restrictions

Import Permit for the State of Hawaii

If shipping to the U.S. state of Hawaii, you must provide either an import permit or documentation stating that an import permit is not required. We cannot ship this item until we receive this documentation. Contact the Hawaii Department of Agriculture (HDOA), Plant Industry Division, Plant Quarantine Branch to determine if an import permit is required.


Frequently Asked Questions


Curated Citations

Thomas EK, et al. Further characterization of Raccoonpox virus. Arch. Virol. 49: 217-222, 1975. PubMed: 813616

Herman YF. Bact. Proc. 64th Annual Meeting, ASM : 117, 1964.

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