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Streptococcus mutans Clarke (ATCC® 700610)

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Strain Designations: UA159 [UAB577]  /  Type Strain: no  /  Biosafety Level: 1

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Verified By Whole-genome Sequencing
Strain Designations UA159 [UAB577]
Transformation host
Child with active caries, 1982
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Antigenic Properties Serotype c
Product Format freeze-dried
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Preceptrol® no
Genome Sequenced Strain

Streptococcus mutans UA159, complete genome.

Type Strain no
Antigenic Properties Serotype c
Antibiotic Resistance
Sensitive to erythromycin
Sensitive to rifampin rifampicin, rifamycin AMP
Sensitive to spectinomycin actinospectacin
Sensitive to streptomycin
Genome sequenced strain
sensitive to erythromycin
sensitive to rifampin rifampicin, rifamycin AMP
sensitive to spectinomycin actinospectacin

sensitive to streptomycin

Component of MSA-1000, MSA-1001, MSA-1002, MSA-1003, MSA-2002, and MSA-2003.

Medium ATCC® Medium 44: Brain Heart Infusion Agar/Broth
Growth Conditions
Temperature: 37°C
Atmosphere: 5% CO2 or aerobic
Name of Depositor PW Caufield
Child with active caries, 1982

Burne RA, et al. Cariogenicity of Streptococcus mutans strains with defects in fructan metabolism assessed in a program-fed specific-pathogen-free rat model. J. Dent. Res. 75: 1572-1577, 1996. PubMed: 8906125

Quivey RG Jr., et al. Acid adaptation in Streptococcus mutans UA159 alleviates sensitization to environmental stress due to RecA deficiency. FEMS Microbiol. Lett. 126: 257-261, 1995. PubMed: 7729669

Tao L, et al. Transformation efficiency of EMS-induced mutants of Streptococcus mutans of altered cell shape. J. Dent. Res. 72: 1032-1039, 1993. PubMed: 8496476

Wexler DL, et al. Characteristics and cariogenicity of a fructanase-defective Streptococcus mutants strain. Infect. Immun. 60: 3673-3681, 1992. PubMed: 1500176

Murchison HH, et al. Transformation of Streptococcus mutans with chromosomal and shuttle plasmid (pYA629) DNAs. Infect. Immun. 54: 273-282, 1986. PubMed: 3021626

Ajdic D, et al. Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen.. Proc. Natl. Acad. Sci. USA 99: 14434-14439, 2002. PubMed: 12397186

Page W Caufield, personal communication

Cross References

Nucleotide (GenBank) : AE014133 Streptococcus mutans UA159, complete genome.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation
  1. Accessing genome sequencing data

    Date Updated: 9/30/2019

  2. Criteria for reference quality genomes

    Date Updated: 9/30/2019