For thousands of years, pathogens originating from animal reservoirs have been responsible for numerous outbreaks among humans. These diseases, known as zoonotic diseases or zoonoses, are estimated to make up more than 60% of known infectious diseases. Within the last century, we have seen an alarming number of new zoonoses emerge that have resulted in globally devastating outbreaks such as Ebola, severe acute respiratory syndrome, avian influenza, Middle East respiratory syndrome, Zika fever, and the ongoing COVID-19 pandemic. These and other zoonotic diseases have had a disastrous impact on public health and the economy, resulting in high morbidity and mortality rates in human and animal populations; strain on healthcare resources and high medical costs; disruptions in trade, transportation, and manufacturing; unemployment; and labor shortages.
The frequency of zoonotic disease transmission has been increasing over time—it is believed that as many as 3 out of every 4 new diseases in humans come from an animal source. It is therefore inevitable that we will continue to see emerging and re-emerging zoonotic diseases in the future. At ATCC, it is our mission to support global health by providing researchers with the resources needed to prevent, detect, and respond to infectious disease outbreaks. As in our response to the COVID-19 pandemic, we will partner with the global research community to acquire, authenticate, maintain, and distribute the clinically relevant pathogens needed to respond to emerging zoonotic diseases.
Resources for zoonotic diseases of concern in the United States
Explore our growing collection of genomic and synthetic RNA, heat-inactivated materials, and antibodies that support coronavirus research.
ATCC provides authenticated genomic DNA prepared from a variety of Yersinia pestis strains to support your research.
Our extensive portfolio includes both species of Salmonella, the six S. enterica subspecies, and over 100 different serovars.
Our portfolio includes in vivo and cell culture–adapted strains, genomic and synthetic RNA, heat-inactivated and high-titer preparations, and host cells.
Support your Lyme Disease research with fully authenticated Borrelia burgdorferi strains and genomic DNA from ATCC.
We offer both in vivo and cell culture–adapted Rabies virus strains to support your essential research.
Support your West Nile virus research with authenticated strains and cell lines from ATCC. We also offer synthetic RNA, which can be used in a BSL-1 facility!
Explore our collection of animal-derived Influenza strains and related genomic RNA and monoclonal antibodies.
How are zoonotic pathogens transmitted from animals to humans?
Zoonotic pathogens are able to spread to humans through any circumstances involving contact with or consumption of animals or animal products. These transmission pathways can be affected by a variety of drivers such as international travel, changes in the agricultural and food industries, urbanization and destruction of natural habitats, or climate change.
- Direct contact – Coming into contact with the bodily fluids (eg, saliva, blood, urine, feces, mucous, respiratory aerosols) from an infected animal. Examples include animal scratches or bites and the handling of domestic and agricultural animals.
- Indirect contact – Coming into contact with inanimate objects or surfaces that have been contaminated. Examples include bedding, brushes, obstetrical equipment, food and water dishes, and barns.
- Vector-borne – Being bitten by a hematophagous arthropod (eg, mosquitoes, fleas, ticks) that previously acquired a pathogen from an infected animal.
- Ingestion – Consuming contaminated food or water. This can occur if animal products such as meat or milk are not cooked or pasteurized properly before consumption or if raw fruits and vegetables are contaminated with fecal matter.
ATCC offers a wide range of microorganisms and nucleic acids that support research on prevalent vector-borne diseases such as Zika, chikungunya, West Nile fever, and Lyme disease. Our high-quality, authenticated reference materials are ideal for use in the development and evaluation of novel vaccines, innovative therapeutics, and rapid diagnostic tools.View all vector-borne pathogens
Respiratory pathogens that emerged from animal reservoirs such as SARS-CoV-2, MERS-CoV, SARS-CoV, and Influenza A virus (H1N1) have resulted in significant outbreaks that have led to numerous fatalities. To support critical research on these pathogens, ATCC provides authenticated strains, heat-inactivated materials, quantitative nucleic acids, and antibodies.View all respiratory pathogens
Enteric diseases are often acquired through the consumption of contaminated food and water or contact with infected animals or fecal matter. To prevent the spread of disease, effective food testing and sanitation practices are needed. ATCC supports this area of research by providing a variety of authenticated microorganisms known to cause disease in humans.View all enteric pathogens
Learning from Zika: Preparing for the Next Outbreak
Synthetic West Nile Virus RNA
Quantitative synthetic RNA for West Nile virus for use in assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance.Get the RNA
Explore the use of this strain as a challenge virus in the rapid fluorescent focus inhibition technique (RFFIT) for the determination of rabies neutralizing antibody levels.Order now
Genomic RNA from SARS-CoV-2
Genomic RNA derived from the "UK variant" B.1.1.7. This strain was isolated from a nasopharyngeal swab in California.Get it now
SARS-CoV-2 Variant B.1.351 (Beta)
Heat-inactivated preparation of strain USA/MD-HP01542/2021. This strain was isolated from a clinical specimen in Maryland.Get it now
Enhance your Lyme disease research with the genome sequenced type strain of Borrelia burgdorferi.Order Today
Zika virus, Heat Inactivated
Heat-inactivated preparation of Zika virus strain PRVABC59 for use as a positive control in molecular assays designed to detect Zika virus.Get it now
Quantitative Synthetic RNA from Chikungunya virus
Quantitative Synthetic RNA from the Chikungunya virus to help with your infectious disease research.Order Today
Salmonella enterica subsp. enterica serovar Typhimurium
Bacterial pathogen with applications in the production of live, avirulent vaccines and enteric disease research.Get the strain
Synthetic Zika virus RNA
Develop your next assay with quantitative synthetic preparations.Get the RNA