Alert icon

Important Holiday Shipping Schedule Update


ATCC will be closed Wednesday, December 24, 2025 to Thursday, January 1, 2026. Please be advised you can still submit orders for products during this time, but shipping will resume on Friday, January 2, 2026.


To ensure shipping before the ATCC holiday closing period, please reference the shipping schedule below:


  • Last shipping day for Domestic orders is Friday, December 19, 2025 (Room temperature items shipping only as no frozen item shipments on Fridays. Frozen/ dry ice shipments resumes January 2, 2026).

  • Last shipping day for International orders is Friday, December 12, 2025.

  • Shipping resumes January 2, 2026 for orders submitted after December 19, 2025.

Contact us
ATCC 100 Years Logo Anniversary ATCC 100 Years Logo Anniversary Cart 0
  • Careers
  • Support

Clinical Cancer Models

Green and red conditionally reprogrammed organoid cells.

Get closer to in vivo with clinical cancer models

In collaboration with the Human Cancer Models Initiative (HCMI), ATCC offers researchers patient-derived cancer models taken from tumor biopsies. The heterogeneity of these models, combined with open-access, next-generation sequencing and clinical data, provide a highly accurate and well-characterized representation of the original tumor. Use these models for translational cancer research and to evaluate targeted candidate therapies in preclinical studies.

The current collection of clinical cancer models includes:

  • Skin
  • Brain
  • Esophagus
  • Stomach
  • Bronchus and lung
  • Bone
  • Kidney
  • Connective tissue

Next-generation research tools

Green ECAD organoid cells.

Next-generation cancer models

ATCC has collaborated with the HCMI to distribute 1000 new human cancer models. Through this initiative, advanced culture methods are being used to generate novel primary tissue–derived models from cancers that are underrepresented by existing cell lines. Download the presentation for an overview of the HCMI and the technologies driving the development of these next-generation models.

View the Presentation
DNA helix made of green and yellow puffy balls.

Search the HCMI catalog

The HCMI catalog is available from the NCI as a resource to the research community. Users are able to query the continuously updated resource and access information on all the available next-generation models developed by the HCMI. Within the catalog, users can search by patient demographics, tumor, and model elements including diagnosis age, sex, treatment information, clinical tumor diagnosis.

Search HCMI Data

Explore clinical cancer models

Refine by