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Streptomyces griseus subsp. griseus (Krainsky) Waksman and Henrici (ATCC® 10137)

Strain Designations: 4 [BUCSAV 7, Boots FD40, NCIB 8232, NCTC 6961]  /  Type Strain: no  /  Biosafety Level: 1

Permits and Restrictions

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Strain Designations 4 [BUCSAV 7, Boots FD40, NCIB 8232, NCTC 6961]
Produces cytochrome P450 and glutaminase.
Transformation of pergolide to pergolide sulfoxide and of 1',2'-dihydrorotenone.
Derived from existing strain
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Preceptrol® yes
Type Strain no
Medium ATCC® Medium 1877: ISP Medium 1
ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26°C
Atmosphere: Aerobic
Name of Depositor SA Waksman
Derived from existing strain

Sariaslani FS, Rosazza JP. Biotransformations of 1',2'-dihydrorotenone by Streptomyces griseus. Appl. Environ. Microbiol. 49: 451-452, 1985. PubMed: 3920966

Yokotsuka T, et al. Hydrolysis of glutamine within foods and beverages to glutamic acid. US Patent 3,717,470 dated Feb 20 1973

Proc. Soc. Exp. Biol. Med. 55: 66-69, 1944.

Kunz DA, Sariaslani SF. Process for inducing cytochrome P-450 enzymes in Streptomyces bacteria and determining the mutagenicity of chemicals. US Patent 5,674,714 dated Oct 7 1997

Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155

derived from Waksman's original streptomycin-producing strain 3463

Cross References

Nucleotide (GenBank) : X17368 S. griseus 5S rRNA.

Nucleotide (GenBank) : X55551 S.griseus saf gene.

Nucleotide (GenBank) : X74868 S.griseus gene for glutamic acid specific protease.

Nucleotide (GenBank) : M64471 Streptomyces griseus (ATCC 10137) trypsin (sprT) gene, complete cds.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation