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Purple yellow and green Caco2 intestinal epithelial cells.

Molecular Signature Panels: Powerful Tools for the Genomics Age

Dec 05, 2013 at 12:00 PM ET

Abstract

Want to bring your research into the genomics age? In this webinar, we will describe the ATCC molecular signature panels, which were generated by combining together authenticated cell lines that contain critical gene copy number changes and site mutations identified by next-generation sequencing. These panels focus on key components of cell signaling pathways. The gene expression, protein expression, and cellular localization of EGFR, AKT, PI3K, PTEN, p53, RAS, RAF, ERK, MYC, and MET were studied and compared within a large number of cell lines with various genetic backgrounds.

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Presenter

Fang Tian, headshot.

Fang Tian, PhD

Lead Scientist, ATCC Cell Systems

Dr. Fang Tian, Lead Scientist, head of the Translational Cell Biology Group for ATCC Cell Systems, has extensive experience in cell biology and molecular biology. She oversees human, animal cell lines and hybridomas, and product development in the Cell Biology General Collection at ATCC. Dr. Tian was a research fellow in Massachusetts General Hospital, Harvard Medical School. She conducted postdoctoral research at the Hillman Cancer Institute of UPMC.