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ATCC® Cell Line Land: An RNA-seq Reference Database for Authenticated Materials

Poster
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Bio-IT World Conference & Expo

Boston, Massachusetts, United States

May 16, 2023

Abstract

Biomedical research has struggled with reproducibility issues, often due to the use of poorly documented cell lines. To address this, ATCC has partnered with QIAGEN to create a reference database of whole transcriptome data for over 3,000 authenticated ATCC human and animal cell lines. Join our poster presentation to learn about our standardized laboratory and bioinformatics workflows and to explore our data from our initial profiling of ~200 cell lines.

Download the poster to learn about our bioinformatics workflow for the whole-transcriptome analysis of cell lines

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Presenter

Amy Reese, headshot

Amy L. Reese, MS

Bioinformatician, Sequencing and Bioinformatics Center, ATCC

Amy Reese is a Bioinformatician with the Sequencing and Bioinformatics Center at ATCC. She has played a vital role in ATCC’s RNA sequencing collaboration with QIAGEN to create the ATCC Cell Line Land, an RNA-seq reference database for authenticated materials. Amy’s primary responsibility is to oversee and analyze all data for this collaboration; over 900 datasets have been shared with QIAGEN to-date. Amy’s other responsibilities include developing novel internal pipelines for the analysis of microorganisms for publication to the ATCC Genome Portal and performing additional RNA-seq analyses for other external collaborators, such as the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and Virginia Tech’s Center for Emerging, Zoonotic, and Arthropod-borne Pathogens (CEZAP).

Before joining ATCC in 2021, Amy held a position as a Virology Senior Research Associate at the National Biological Threat Characterization Center (NBTCC) of the National Biodefense Analysis and Countermeasures Center (NBACC). There, Amy worked as technical lead on projects working directly with high containment pathogens such as Ebola virus and SARS-CoV-2, and trained new employees in the BSL-2, 3, and 4 laboratories. Amy holds a Bachelor of Science in Biology, a Master of Science in Biology, and a Master of Science in Bioinformatics. 

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Learn more about the ATCC Cell Line Land Database

Learn more