Pimelobacter simplex (Jensen) Suzuki and Komagata (ATCC® 6946)

Strain Designations: NCTC 4215 [BUCSAV 385, CDA 835, FHP 534, NCIB 8929]  /  Type Strain: yes  /  Biosafety Level: 1

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Deposited As Corynebacterium simplex Jensen
Strain Designations NCTC 4215 [BUCSAV 385, CDA 835, FHP 534, NCIB 8929]
Application
Degrades levulinic acid
Produces 3-keto-delta-1,4 steroids
Produces 5'-nucleotides
Produces 7-cyano steroids
Produces oxoalkylxanthines oxoalkylxanthine
Produces pregnadienes
Produces 5'-nucleotides by growth on hydrocarbons and subsequent degradation of intracellular RNA at alkaline pH
Reduction of 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14, 17-dione
Reduction of 4-chloro-1-(4-fluorophenyl)butan-1-one
Dehydrogenation of Reichstein's compound S and hydrocortisone
Isolation
Rice soil
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Preceptrol® no
Type Strain yes RefValidation list no. 12. Int. J. Syst. Bacteriol. 33: 896-897, 1983. , RefO'Donnell AG, et al. Lipids in the classification of Nocardioides: reclassification of Arthrobacter simplex (Jensen) lochhead in the genus Nocardioides (Prauser) emend. O'Donnell et al. as Nocardioides simplex comb. nov.. Arch. Microbiol. 133: 323-329, 1982. PubMed: 7171289, RefSkerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.
Medium ATCC® Medium 3: Nutrient agar or nutrient broth
Growth Conditions
Temperature: 26.0°C
Name of Depositor NCTC
Chain of Custody
ATCC <<--NCTC<<--H.L. Jensen
Isolation
Rice soil
References

Nesemann G, et al. Microbiological process for the preparation of oxoalkylxanthines. Canadian Patent 1,022,867

Nobile A. Process for production of dienes by corynebacteria. US Patent 2,837,464 dated Jun 3 1958

Nakao Y, Kuno M. Method for the production of 5'-nucleotides. US Patent 3,652,395 dated Mar 28 1972

Badia DJ, Sardinas JL. Oxidation of steroid compounds in presence of antibiotics. US Patent 3,010,876 dated Nov 28 1961

Bowers A, Ringold HJ. 7-Cyano steroids. US Patent 3,050,534 dated Aug 21 1962

Ueno T, Harada M. Method for removing levulinic acid by microorganisms. US Patent 3,663,368 dated May 16 1972

Nesemann G, et al. Mikrobiologisches Verfahren zur Herstellung von Oxoalkylxanthinen. German Federal Republic Patent 2,302,772

Casas-Campillo C. Process for the transformation of steroids using a mutant strain of Arthrobacter (Corynebacterium) simplex. US Patent 3,264,194 dated Aug 2 1966

Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971

Validation list no. 12. Int. J. Syst. Bacteriol. 33: 896-897, 1983.

Proc. Linn. Soc. N.S.W. 58: 181, 1933.

Montes MC, Magana I. Delta'-dehydrogenation of steroids by Arthrobacter simplex immobilized in calcium polygalacturonate beads. J. Ind. Microbiol. 8: 259-264, 1991. PubMed: 1367800

O'Donnell AG, et al. Lipids in the classification of Nocardioides: reclassification of Arthrobacter simplex (Jensen) lochhead in the genus Nocardioides (Prauser) emend. O'Donnell et al. as Nocardioides simplex comb. nov.. Arch. Microbiol. 133: 323-329, 1982. PubMed: 7171289

Patel RN, et al. Microbial reduction of 1-(4-fluorophenyl)-4-[4-(5-fluoro-2-pyrimidinyl)-1-piperazinyl]butan-1-one. Biotechnol. Appl. Biochem. 17: 139-153, 1993. PubMed: 8166884

Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.

Cremers FP, et al. An autosomal homologue of the choroideremia gene colocalizes with the usher syndorme type II locus on the distal part of chromosome 1q. Hum. Mol. Genet. 1: 71-75, 1992. PubMed: 1301160

Validation list no. 12. Int. J. Syst. Bacteriol. 33: 896-897, 1983.

O'Donnell AG, et al. Lipids in the classification of Nocardioides: reclassification of Arthrobacter simplex (Jensen) lochhead in the genus Nocardioides (Prauser) emend. O'Donnell et al. as Nocardioides simplex comb. nov.. Arch. Microbiol. 133: 323-329, 1982. PubMed: 7171289

Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.

Cross References

Nucleotide (GenBank) : M16174 P.simplex 5S rRNA.

Nucleotide (GenBank) : M37693 Arthobacter simplex small subunit ribosomal RNA.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
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