Streptomyces cattleya (ATCC® 35852)

Strain Designations: NRRL 8057 [MA-4297]  /  Type Strain: no  /  Biosafety Level: 1

Strain Designations NRRL 8057 [MA-4297]
Produces 3-ethynylserine beta-ethynylserine
Produces 4-fluorothreonine
Produces 8-epi-thienamycin
Produces fluoroacetic acid monofluoroacetate
Produces northienamycin
Produces thienamycin
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Preceptrol® no
Type Strain no
Medium ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26.0°C
Name of Depositor NRRL
Chain of Custody
ATCC <<--NRRL<<--Merck & Co., Inc. MA-4297

Sanada M, et al. Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer Streptomyces cattleya. J. Antibiot. 39: 259-265, 1986. PubMed: 3082840

Sanada M, et al. beta-Ethynylserine, an antimetabolite of L-threonine, from Streptomyces cattleya. J. Antibiot. 39: 304-305, 1986. PubMed: 3082841

Kahan JS, et al. Antibiotics. US Patent 3,950,357 dated Apr 13 1976

Kahan FM, et al. Thienamycin production. US Patent 4,006,060 dated Feb 1 1977

Datta R, Wildman GT. Process for isolating thienamycin. US Patent 4,168,268 dated Sep 18 1979

Treiber LR, Gullo VP. Process for purifying thienamycin. US Patent 4,198,338 dated Apr 15 1980

Kahan JS, Kahan FM. Process for enzymatic deacylation of antibiotics. US Patent 4,282,322 dated Aug 4 1981

Kahan FM, et al. Culture of Streptomyces cattleya. US Patent 4,304,867 dated Dec 8 1981

Wilson KE, Kempf AJ. Fermentation process for (5R, 6S,8S)-3-(2-aminoethylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid. US Patent 4,335,212 dated Jun 15 1982