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Homo sapiens, human
Clone type
Molecular biology
Product format
Shipping information
bacteria-free lysate
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Detailed product information


Specific applications
Codominant inheritance was observed in 3 informative families (39 children).


Restriction digests of the clone give the following sizes (kb): BamHI--20.0, 9.0, 5.0, 4.3, 1.8, 1.7, 1.7, 0.7; BglII--25.0, 7.0, 3.2, 3.0, 2.4, 1.5, 0.68; PvuI--20.0, 12.0, 8.0; HindIII--21.0, 18.0, 4.3, 0.8; SmaI--20.0, 19.0, 5.6.
The insert contains the following sites separated by (kb)(approx): SalI, MboII- 1.5- BamHI- 1.7- BamHI- 1.7- BamHI- 4.3- BamHI- 1.8- BamHI- 0.65- BamHI- 5.0- SmaI- 0.6- BamHI- 0.7- MboII, SalI.
Codominant inheritance was observed in 3 informative families (39 children).
The 1.6 kb BamHI fragment contains exon 7 and 3' sequences. Exon 7, which has been sequenced, encodes the last 64 amino acids and includes 1.2 kb of 3' non-coding sequence.
The BamHI 1.6 doublet detects the TaqI RFLP associated with DRD2.
Use standard hybridization conditions with the addition of human placental DNA to block repeat sequences. Washing conditions are standard with a final wash at 0.1 x SSC, 0.1% SDS, 65C.
Enzyme(s) not detecting polymorphism: 31 enzymes.
Mycoplasma contamination
Not detected

Vector information

Construct size (kb)

Insert information

Insert size (kb)
Type of DNA
Insert source
Insert tissue
Gene product
dopamine receptor D2 [DRD2]
A1, B1, B2, A2


O Civelli, DK Grandy
Cross references
GenBank M29066
GenBank 170941

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Permits & Restrictions

Import Permit for the State of Hawaii

If shipping to the U.S. state of Hawaii, you must provide either an import permit or documentation stating that an import permit is not required. We cannot ship this item until we receive this documentation. Contact the Hawaii Department of Agriculture (HDOA), Plant Industry Division, Plant Quarantine Branch to determine if an import permit is required.



Curated Citations

Grandy DK, et al. The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP. Am. J. Hum. Genet. 45: 778-785, 1989. PubMed: 2573278

Grandy DK, et al. Cloning of the cDNA and gene for a human D2 dopamine receptor. Proc. Natl. Acad. Sci. USA 86: 9762-9766, 1989. PubMed: 2532362

Olivier Civelli, personal communication

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