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Application notes

Advanced biological models and credible reference standards enable greater specificity and functionality to the researcher’s toolkit. Browse our growing collection of application notes for access to in-depth data on the development and validation of these products and to explore proof-of-concept studies focused on their various applications.

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20101222-01 Universal Mycoplasma Detection Kit.jpg Application note

Assay Validation of a PCR-based Mycoplasma Detection Kit

In this application note, we demonstrate that the Universal Mycoplasma Detection Kit provides a reliable tool for routine mycoplasma screening.

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Digitally colorized transmission electron micrograph showing several spherical virions from a 2009 pandemic influenza A (H1N1) virus isolate. The viral particles are clustered together and surrounded by distinct surface spikes, highlighting characteristic structural features of the influenza virus as observed using electron microscopy. Application note

Performance Assessment of ATCC® Oseltamivir-Resistant Influenza A/H1N1pdm09 Strains as Analytical Reference Materials for Diagnostic Surveillance

In this application note, we experimentally verified the performance of oseltamivir-resistant strains in mutation-specific quantitative RT-PCR assays.

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iStock_000085783477_Double_ZikaVirus_Color.jpg Application note

Performance Assessment of ATCC® Quantitative Synthetic Zika Virus RNA as an Analytical Reference Material

In this application note, we evaluate a quantitative synthetic Zika virus RNA analytical reference material as a robust, lineage-agnostic reference material for qRT-PCR assay development and validation.

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A digitally colorized transmission electron micrograph shows Avian Influenza A (H5N1) virus particles highlighted in gold within infected Madin‑Darby Canine Kidney (MDCK) epithelial cells shown in green. Numerous elongated and spherical virions are visible among cellular membranes, illustrating viral replication inside host cells. Application note

Performance Assessment of Avian Influenza Virus Analytical Reference Materials for Diagnostic Surveillance: Subtypes H5N1, H7N9, H7N7, H5N6, and H9N2

This application note demonstrates the development and validation of quantitative synthetic RNA reference materials for Avian influenza subtypes H5N1, H7N9, H7N7, H5N6, and H9N2.

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Monkeypox virus Application note

Performance Assessment of ATCC® Quantitative Synthetic Analytical Reference Material for Human Monkeypox Virus (hMPXV)

In this application note, we evaluate the performance of the synthetic hMPXV analytical reference material and demonstrate its reliability as a safe, BSL‑1 positive control compatible with multiple published qPCR assays targeting both Clade I and Clade II monkeypox virus.

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 Transparent bubble of Chlamydia bacteria. Application note

Performance Assessment of Quantitative Synthetic Chlamydia trachomatis LGV I, II, and III Reference Materials for qPCR Applications

This application note demonstrates the development and validation of quantitative synthetic DNA reference materials for Chlamydia trachomatis LGV serovars I–III.

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