Subscribe
Date
Past
2012
2013
2014
2015
2016
2017
Upcoming

Angio-Ready

An improved in vitro model of angiogenesis

6/8/2017

Time: 12:00 PM Eastern Standard Time

Abstract:

Angiogenesis is a multi-step physiological process that is involved in a large number of normal and disease state processes. In this webinar, we will introduce the Angio-Ready™ Angiogenesis Assay System, an in vitro co-culture system for measuring angiogenesis. Angio-Ready™ consists of an assay-ready mixture of an hTERT-immortalized human aortic endothelial cell line (TeloHAEC-GFP) and an hTERT-immortalized adipose-derived mesenchymal stem cell line (hTERT-MSC) in a specially formulated medium. Both cell lines have been well-characterized to verify that they retain the most important characteristic of their parental counterparts. The new co-culture system forms functional tubular structures in less than 7 days and responds appropriately in a dose dependent manner to known agonists and inhibitors of angiogenesis. Thus, Angio-Ready™ is a ready-to-use, time-saving, high-throughput model for screening drugs or biomolecules for their effect on angiogenesis in cancer, toxicology, diabetes, cardiovascular disease, wound healing, and other pathologies.

Key Points:

  • Angio-Ready™ is a ready-to-use, scalable assay system for angiogenesis
  • Live imaging is possible with this in vivo-like model consisting of fine tubular structures formed in less than 7 days
  • The formation of vascular tubules responds appropriately to agonists and inhibitors of angiogenesis