Drug Discovery

Authenticated, physiologically relevant cell models and clinically significant microorganisms are critical tools for drug discovery and development. These types of physical laboratory standards allow investigators to rapidly and reliably identify potential drug targets and screen compounds for efficacy and safety.

From target selection to toxicity screening, ATCC is devoted to providing researchers and pharmaceutical developers with essential solutions for their drug discovery and development processes. Explore our resources to learn more about the application of ATCC reference strains and cell models that propel new scientific discoveries.

Featured Content

Neurotoxicity Testing of Neural Progenitor Cells

A study describing the characterization and validation of a model system comprising neural progenitor cells for use in drug discovery and toxicology screening.

Using CRISPR to Develop Isogenic Cell Models

Explore how CRISPR gene-editing technology can be used to create isogenic cell lines that are relevant for drug discovery and development.

Organoid Culture Tutorial and Guide

Discover a video tutorial and culture guide that contain everything you need to know about the initiation, expansion, and cryopreservation of organoids in embedded 3D culture.

CRISPR-edited Isogenic Cell Models

Learn how ATCC uses CRISPR technology to create precisely gene-edited isogenic cell models for drug screening applications.

Hematopoietic Progenitor Cell Models

Explore more on the development of hematopoiesis models using bone marrow cells, peripheral blood monocytes, and primary peripheral blood mononuclear cells.

Enhance Pneumococcal Vaccine Development

A discussion on the importance of purified serotype-specific pneumococcal polysaccharides in vaccine development, assay validation, and epidemiology tracking.

Alternative Approaches for Treating Infections

An evaluation on the advantages and disadvantages of using bacteriophage therapy to treat multidrug-resistant bacterial infections.

Clinically Relevant AMR Reference Materials

A discussion on the emerging threat of antimicrobial resistance and the importance of clinically relevant reference strains in assay development and drug discovery.

Carbapenem-resistant Enterobacteriaceae

 Learn more about the emergence of multidrug-resistant infections with a particular emphasis on the global spread of carbapenem-resistant Enterobacteriaceae strains.