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In this webinar Diversigen, Inc. scientist Dr. Tasha Santiago-Rodrigues will discuss the field of viral metagenomics, focusing on the following key points:

  • Implementation of viral standards and controls can help determine biases that could be potentially introduced at different stages of a viral metagenomics pipeline.
  • Identification of biases in a viral metagenomics study provides the opportunity to troubleshoot and benchmark reagents and analysis tools. 
  • Viral standards may evolve to mimic simple and more complex viral communities in diverse environments.

In this webinar, ATCC microbiologist Britany Tang will give an overview of the novel coronavirus SARS-CoV-2 that presents these key points:

  • Understanding the nature of the disease (COVID-19)
  • Understanding what other coronaviruses tell us about SARS-CoV-2 history, genomics, and epidemiology
  • Explaining the advancements in scientific and clinical research and development and how ATCC is contributing to the fight against COVID-19

Brian Shapiro, Ph.D., is adept at developing assays that incorporate primary cells. Join this webinar to hear this ATCC expert cover the following key points:

  • Differentiated iPSCs lend the ability to run large toxicity studies and drug screens on highly biologically relevant cells.
  • ATCC iPSCs were used as the source for three types of differentiated cells: CD34+ progenitors, mesenchymal stem cells (MSCs), and monocytes.
  • ATCC R&D scientists have generated in-depth data showing the iPSC-derived cells can be incorporated into immunoassays and further differentiated into cell types such as osteocytes, chondrocytes, and adipocytes.

Steve Budd, MBA, has extensive experience with culturing hard-to-grow cell lines and primary cells. Watch this webinar to hear this ATCC expert cover the following key points:

  • There are many cell models; choosing the correct one for your workflow will add efficiency and productivity to your work.
  • When culturing specialty cells, such as stem cells or primary cells, certain considerations regarding the choice of media and reagents must be taken.
  • Using misidentified or cross-contaminated cell lines in experiments can invalidate experimental results; therefore, authenticating cell lines should be part of your cell culture workflow.
  • Mycoplasma infection can chronically affect the well-being of cells in culture without being detected by visual observation; multiple screening methods can be used to identify contamination.
  • Tools such as proliferation assays and cryo-containers can aid the maintenance of cell health.


Dr. Elizabeth Gillies is well-versed in using CRISPR/Cas9 genome-editing technology for creating advanced cell-based models. Watch the presentation to learn how this cutting edge technology was used to enhance virus production in ATCC cell lines

  • Most viral vaccines are manufactured in large-scale tissue culture systems using historical cell lines that are approved for vaccine manufacturing.
  • ATCC used CRISPR/Cas9 gene-editing techniques to increase the viral production efficiency of some of these historical cell lines.
  • These enhanced virus-producing cell lines have the potential to significantly reduce the costs associated with generating viral vaccines and high-titer viral stocks.

In this webinar, we will spark a discussion from a highly distinguished panel from different domains of the industry. Together, we will explore the three key areas of scientific research that play a critical role in the reproducibility science, with the aim to arrive at actionable ideas that every scientist can employ today to improve reproducibility in their own research.

Balsam Shawky, MS, and Brian Shapiro, PhD, are experts in the authentication and characterization of cell lines. Join this webinar to explore how ATCC is raising credibility in science by pioneering cutting-edge solutions that support cell line verification.

Key points:

  • Cell line authentication is a critical requirement to receive funding for research, publish papers in scientific journals, and validate in vitro studies for preclinical testing
  • ATCC offers human and mouse STR profiling services for cell line authentication
  • The mouse STR profiling method was developed by NIST in collaboration with ATCC and 10 independent laboratories

Dr. Elizabeth Gillies is well-versed in using CRISPR/Cas9 genome-editing technology for creating advanced cell-based models. Watch the presentation to learn how this cutting edge technology was used to enhance virus production in ATCC cell lines

  • Most viral vaccines are manufactured in large-scale tissue culture systems using historical cell lines that are approved for vaccine manufacturing.
  • ATCC used CRISPR/Cas9 gene-editing techniques to increase the viral production efficiency of some of these historical cell lines.
  • These enhanced virus-producing cell lines have the potential to significantly reduce the costs associated with generating viral vaccines and high-titer viral stocks.

Antimicrobial Resistance II

Arm Your Lab in the Fight Against Superbugs

2/27/2020

This second part of a two-part webinar series on antimicrobial resistance, presented by ATCC Scientist Christine Fedorchuk, will provide these key takeaways:

  • Understanding the nature of the problem: explaining the biggest challenges hindering advancement such as financial deficits, implementation of surveillance or new therapies, and the speed of resistance outpacing the speed of scientific research.
  • Explaining progress: scientific and clinical advances, how organizations are contributing to the fight against AMR, and how ATCC is contributing to the fight against AMR.

In this webinar GMU Director of the Laboratory of Molecular Virology Fatah Kachanshi and ATCC Lead Biologist Heather Branscome will cover these key points:

  • Extracellular vesicles (EVs) such as exosomes are critical mediators of intercellular communication. The diverse biological cargo that is associated with these vesicles is believed to mediate the pleiotropic effects of EVs.
  • Damaging EVs contain viral non-coding RNAs and other viral proteins. These EVs can exert deleterious effects on recipient cells; further characterization of damaging EVs may serve for diagnostic purposes.
  • Reparative EVs can contribute to various biological processes ranging from normal cellular development to the repair of damaged and/or diseased tissue. Because of their broad regenerative properties, stem cell EVs are being evaluated as potential replacements for stem cell therapy.