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Matching Algorithm

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The matching criterion is based on an algorithm

Compare the number of shared alleles between two cell line samples, expressed as a percentage

Understanding the matching algorithm

The matching criterion is based on an algorithm that compares the number of shared alleles between two cell line samples, expressed as a percentage. Cell lines with ≥90% match have a high probability of being related, ie, derived from a common ancestry and traceable to a single donor or identical twins. Cell lines with between a 80% to 90% match require further analysis for authentication of relatedness. Two algorithms are available for searching profiles in the ATCC database. While the Tanabe algorithm is now the recommended algorithm for STR profiling, the Masters algorithm remains useful when trying to determine the identity of a contaminating cell line.

Explore STR database resources

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STR Authentication: Using the ATCC public STR Database

Find out how to search the STR public database

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DNA double helix strands in silver, yellow and green.

STR Profiling Analysis

ATCC's STR profiles help ensure the quality and integrity of human cell lines in the scientific community.

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Search the STR Database

Search the STR database of DNA profiles of all our human cell lines.

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