Paracoccidioides brasiliensis (Splendore) Almeida, anamorph (ATCC® MYA-826)

Strain Designations: Pb01 [01]  /  Product Format: frozen

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Strain Designations Pb01 [01]
RAPD analysis
Biomedical Research and Development Material
Biosafety Level 2
Product Format frozen
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain no
Preceptrol® no
Genome Sequenced Strain


highly virulent
differential expression of proteins PbY20 (by yeast form) and PbM46 (by mycelial form)
protein synthesis patterns
effect of amphotericin B
expression of gp43
differential expression of gene for heat shock protein, Hsp70
RAPD analysis
Genome sequencing strain (University of Brasil, Brasil).
Medium ATCC® Medium 28: Emmons' modification of Sabouraud's agar
Growth Conditions
Temperature: 37.0°C
Name of Depositor CM Soares
Special Collection NCRR Contract
Chain of Custody
ATCC <<--CM Soares<<--M.R.R. Silva 01
clinical isolate, Goiania, Brazil
Cross References

Nucleotide (GenBank) : AF148715 glucan synthase (FKS) gene, complete coding sequence

Nucleotide (GenBank) : U91560 heat shock protein 70 gene, hsp70, complete coding sequence

Complete Genome (GenBank) : ABKH00000000 Paracoccidioides brasiliensis Pb01, whole genome shotgun sequencing project


Pereira M, et al. Molecular cloning and characterization of a glucan synthase gene from the human pathogenic fungus Paracoccidioides brasiliensis. Yeast 16: 451-462, 2000. PubMed: 10705373

Cunha AF, et al. Identification, N-terminal region sequencing and similarity analysis of differentially expressed proteins in Paracoccidioides brasiliensis. Med. Mycol. 37: 115-121, 1999. PubMed: 10361267

Molinari-Madlum EE, et al. Virulence of Paracoccidioides brasiliensis isolates can be correlated to groups defined by random amplified polymorphic DNA analysis. Med. Mycol. 37: 269-276, 1999. PubMed: 10421862

Salem-Izacc SM, et al. Protein synthesis patterns of Paracoccidioides brasiliensis isolates in stage-specific forms and during cellular differentiation. J. Med. Vet. Mycol. 35: 205-211, 1997.

Soares CM, et al. Characterization of Paracoccidioides brasiliensis isloates by random amplified polymorphic DNA analysis. J. Clin. Microbiol. 33: 505-507, 1995. PubMed: 7714219

Jesuino RS, et al. In vitro amphotericin B effects on growth, viability and dimorphism of Paracoccidioides brasiliensis: reversal of the treatment. Microbiol. Immunol. 41: 93-99, 1997. PubMed: 9087951

Mattar-Filho R, et al. Expression of glycoprotein gp43 in stage-specific forms and during dimorphic differentiation of Paraccidioides brasiliensis. J. Med. Vet. Mycol. 35: 341-345, 1997.

da Silva SP, et al. Phase transition and stage-specific protein synthesis in the dimorphic fungus Paracoccidioides brasiliensis. Exp. Mycol. 18: 294-299, 1994.

da Silva SP, et al. Differential expression of an hsp70 gene during transition from the mycelial to the infective yeast form of the human pathogenic fungus Paracoccidioides brasiliensis. Mol. Microbiol. 31: 1039-1050, 1999. PubMed: 10096073

Celia M Soares, personal communication

Wang H, et al. A fungal phylogeny based on 82 complete genomes using the composition vector method. BMC Evol. Biol. 9: 195, 2009.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation