Vaccine Development

Clear vials sealed with silver caps, one vial lying on its side being punctured by syringe.

Together we can prevent devastating epidemics

The continual spread of deadly pathogens coupled with the dwindling supply of antimicrobial treatments necessitates the development of effective prevention methods. However, the development of novel vaccines can be challenged by the incredible variability between microbial strains and the limitations associated with the vaccine manufacturing process.

At ATCC, we believe that it takes the combined efforts of dedicated scientists throughout the world to discover the treatments needed to keep humankind healthy and safe. That’s why we are committed to providing researchers with the virus-producing cell lines, pathogenic microbial strains, and purified pneumococcal polysaccharides needed to support vaccine research and development.

Together, we can work toward preventing and containing the world’s most devastating epidemics. Browse our resources below to discover how ATCC can support your vaccine research.

Vaccine development tools

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Cell lines for enhanced virus production

ATCC used cutting-edge CRISPR/Cas9 gene-editing technology to develop STAT1 knockout and STAT1/BAX double knockout cell lines capable of producing high-titer viral stocks. Discover how these cell models can be used in your vaccine and gene therapeutic development projects.

Learn more about these cell models

Three male scientists walking shoulder to shoulder through lab looking at a tablet held by the middle scientist on the right side. Background shows orange, purple gradient DNA helix on the left side disintegrating into small particles.

Residual host cell DNA testing

ATCC and USP formed a partnership to develop highly characterized and pure genomic DNA analytical reference materials for validating the performance of molecular assays designed to detect and measure residual host cell genomic DNA.

Explore these analytical reference materials

Featured Products

293.STAT1 BAX KO

This STAT1 BAX double knockout HEK-293 cell line exhibits significant increased viral titer and enhanced virus production capability.

Get the cells

This digitally-colorized transmission electron microscopic (TEM) image revealed some of the ultrastructural details exhibited by a small cluster of adenovirus virions. The virions are depicted as purple, spherical structures with a textured surface, clustered together against a light background.

Human adenovirus 5

Genome sequenced reference material for vaccine development and gene therapy.

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Fluorescent microscopy image showing MDCK cells stained with IFITM3 in red, Phalloidin in green, and DAPI in blue. The cells exhibit distinct red puncta indicating the presence of IFITM3, green filamentous structures representing actin filaments stained by Phalloidin, and blue nuclei stained by DAPI. This image was submitted to ATCC photo contest by Christopher Chin.

MDCK.STAT1 KO

For Influenza vaccine production, influenza propagation, and production of high-titer influenza stocks.

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17778_lores Ebola budding from Vero cell _ NIAID.jpg

Vero.STAT1 KO

For viral vaccine production including virus propagation, production of high-titer viral stocks, and rescue of clinical viral isolates.

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Several floating strings of purple drug-resistant Streptococcus pneumoniae spheres.

Pneumococcal Polysaccaride Powder Type 19F

Isolated from Streptococcus pneumoniae for vaccine development.

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Vaccine Development

Together we can prevent devastating epidemics