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Abstract:

Optimized cell lines are essential for modeling neurodegenerative diseases such as Parkinson’s disease, screening novel therapeutics for preclinical studies, and testing the neurotoxicity of environmental compounds. Neural progenitor cells (NPCs) derived from induced pluripotent stem cells (iPSCs) are excellent in vitro models as they can be induced to differentiate down all three neural lineages. ATCC has recently added a line of NPCs developed from a donor with Parkinson’s disease to its collection of neurological research tools. This webinar will describe how ATCC NPCs can be differentiated into three neural fates and used in toxicological studies, focusing on the performance of the Parkinson’s disease-derived NPCs.

Key Points:

  • ATCC has a wide range of whole-cell models of Parkinson’s disease
  • NPCs cultured in ATCC Dopaminergic Neuron Differentiation Media express tyrosine hydroxylase and TuJ1
  • Parkinson’s disease patient-derived NPCs can be induced to differentiate into all three major neural lineages
  • Parkinson’s disease patient-derived NPCs can be used to screen compounds for toxicity

SOT 2018

Society of Toxicology

3/12/2018 — 3/15/2018

San Antonio, Texas

Booth: 1422

Approximately 6,500 toxicologists from more than 50 countries are expected to share their research and expertise during the 160+ Scientific Sessions, featuring nearly 2,500 abstracts.


Exhibitor-hosted Session

Advanced In Vitro Solute Carrier Transporter Models for Renal Toxicity Studies and Screening
Presenter: Kevin Grady, BS, ATCC; Chaozhong Zou, PhD, ATCC
Location: 217D
March 14, 2018
10:30 AM – 11:30 AM


Posters

Charles Zou

A New Human Renal Solute Carrier Uptake Model for Drug Toxicity Studies
Presenter: Chaozhong Zou, PhD, ATCC
Abstract Number/Poster Board Number: #1557/P783
Location: CC Exhibit Hall

March 12, 2018
1:30 PM – 3:00 PM

Sheela Jacob, PhD

Comprehensive Gene Expression Analysis and Neurotoxicity Testing of Human iPSCs-Derived Neural Progenitor Cells and Neurons
Presenter: Sheela Jacob, PhD, ATCC
Abstract Number/Poster Board Number: #1425/P530
Location: CC Exhibit Hall

March 12, 2018
3:00 PM – 4:30 PM

3/15/2018 — 3/18/2018

Melbourne

Eradicate Cancer conference will be held in Melbourne 15-17 March 2018. The conference will embrace the latest technologies and clinical advances in cancer research, focusing on current strategies to rejuvenate and reconstruct the immune system of cancer patients.

4/12/2018 — 4/24/2018

Madrid

At the 28th European Congress of Clinical Microbiology and Infectious Diseases (Madrid, Spain, from 21 - 24 April 2018), the world’s leading experts will join the most important congress in infectious diseases, infection control and clinical microbiology to present and discuss the latest results.

4/14/2018 — 4/18/2018

Chicago Illinois

Booth: 1317

The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research.

5/19/2018 — 5/22/2018

Toronto ON

At the 8th annual Cedarlane Life Science & Medical Lab Expo (Toronto, ON, from May 19 – May 22 2018) you can see what’s new in your area of research and chat with industry experts.

6/7/2018 — 6/11/2018

Atlanta GA

Booth: 1510 & 1514

ASM Microbe 2018 (June 7-11, 2017, Atlanta, GA) showcases the best microbial sciences in the world, and provides a one-of-a-kind forum to explore the complete spectrum of microbiology from basic science to translation and application.

7/14/2018 — 7/18/2018

College Park MD

ASTMH 67th Annual Meeting 2018

Precision Medicine Starts Here

10/28/2018 — 11/1/2018

New Orleans LA

The ASTMH Annual Meeting is a five-day educational conference that draws nearly 4,500 attendees -researchers, physicians in global health and tropical and travel disease, military personnel and public health officials from around the world.