Malaria, a debilitating disease caused by Plasmodium parasites, is transmitted to humans through mosquito bites and remains a major public health problem particularly in the tropics. The World Health Organization estimates that in 2021, there were 247 million malaria cases and 619,000 malaria-related deaths globally.1 Malaria used to be a scourge in the USA before it was eliminated in the 1950s through a concerted nationwide environmental program that targeted mosquitoes with the highly effective insecticide called DDT. For decades, the USA has remained malaria-free except for a few sporadic cases of imported malaria. Recent reports of locally transmitted malaria infections in Maryland, Texas, and Florida2 emphasize the need to be vigilant and maintain a vibrant malaria surveillance program at home.