Standardize your gene therapy research with confidence
In the rapidly evolving field of gene therapy, precision and reproducibility are non-negotiable. ATCC's Adenovirus, Adeno-associated virus, and Lentiviral reference materials provide the internationally accepted standards needed for assay validation, vector quantification, and inter-laboratory data harmonization. Whether you're developing cutting-edge therapeutics or refining your QC protocols, these reference materials empower your research with precision and credibility.
- Developed under the guidance of multidisciplinary working groups and leading regulatory experts
- Highly characterized for identity, purity, particle concentration, and infectious titer
- Free from adventitious agents, endotoxins, and mycoplasma
- Backed by extensive documentation and stability data
- Ideal for assay calibration, potency testing, and internal reference standard calibration
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Human Adenovirus Type 5 Reference Material
All new stocks of the reference material will be produced and authenticated at ATCC instead of by an outside working group—that means no more supply limitations when ordering!
Because of the necessary differences in manufacturing between new lots and the original 2001 production, there are a few changes to the reference material as compared to previous stocks. We have provided a comparison for reference.
View a comparison of these productsMitigate risk and maximize impact with standardized viral reference materials
Gene therapies commonly use viral vectors—such as Lentivirus, Adenovirus, and Adeno-associated viruses (AAV2 and AAV8)—to deliver therapeutic genes into patient cells. However, differences in how these vectors are produced and measured can lead to variability in experimental outcomes, making it difficult to compare results across studies and meet regulatory standards.
Standardized viral reference materials help address this issue by serving as benchmarks for assay calibration and performance validation. Carefully characterized for metrics like particle concentration, genome copy number, and infectivity, these materials support consistent quantification and reduce discrepancies in data. This is especially important when working with widely used vectors that have distinct biological properties and clinical applications.
By improving reproducibility and enabling interlaboratory comparisons, viral reference materials play a key role in establishing reliable dosage, potency, and safety profiles. Ultimately, they enhance the credibility and comparability of gene therapy research, supporting both preclinical development and clinical translation.
