Dengue virus type 3 (ATCC® VR-1690)

Classification: Flaviviridae, Flavivirus  /  Product Format: frozen

Classification Flaviviridae, Flavivirus
Agent Dengue virus type 3
Strain Monoclonal Anti-Dengue virus type 3 envelope protein, Clone E9 (produced in vitro)
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions -20┬░C or colder. Repeated freeze-thaw cycles should be avoided.
Comments Antibody Class: IgG1κ
The B cell hybridoma was generated by the fusion of P3X63.Ag. BALB/c mouse myeloma cells with immunized mouse splenocytes.
Name of Depositor MS Diamond, Washington University in St. Louis, School of Medicine
Source Mouse monoclonal antibody prepared against the envelope glycoprotein of Dengue virus type 3 (DEN-3) was purified from clone E9 hybridoma supernatant by protein G affinity chromatography.

Balsitis SJ, et al. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog. 6: e1000790, 2012. PubMed: 20168989

Rajamanonmari R, et al. On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J. Gen. Virol. 90: 799-809, 2009. PubMed: 19264660