Colon Cancer p53 Hotspot Mutation Cell Panel (ATCC® TCP-2020)

Organism: Homo sapiens, human  / 

Organism Homo sapiens, human
Components
LS174T, ATCC CL-188
SW48, ATCC CCL-231
LS123, ATCC CCL-255
LS1034, ATCC CRL-2158
COLO 320DM, ATCC CCL-220
WiDr, ATCC CCL-218
Applications
Biological understanding of top genetic alterations across tumor types
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Type Strain no
Biosafety Level 1
Comments
The Colon Cancer p53 Hotspot Mutation Cell Panel is comprised of 6 select cell lines derived from colon cancer that have been sequenced and validated by ATCC. The panel includes both WT p53 cell lines as well as cultures with p53 hotspot mutations at codons 175, 245, 248, or 273.
Product Format frozen
Storage Conditions LN vapor (less than -130°C) only