Streptomyces rapamycinicus Kumar and Goodfellow (ATCC® 29253)

Strain Designations: AY B-994 [NRRL 5491]  /  Type Strain: yes  /  Biosafety Level: 1

Deposited As Streptomyces hygroscopicus subsp. hygroscopicus (Jensen) Waksman and Henrici
Strain Designations AY B-994 [NRRL 5491]
Application
Produces sirolimus rapamycin
Isolation
Soil, Easter Island
Type Strain yes
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Preceptrol® no
Type Strain yes
Medium ATCC® Medium 1877: ISP Medium 1
ATCC® Medium 334: Oatmeal agar
Growth Conditions
Temperature: 26°C
Atmosphere: Aerobic
Name of Depositor C Vezina
Isolation
Soil, Easter Island
References

Kumar Y, Goodfellow M. Five new members of the Streptomyces violaceusniger 16S rRNA gene clade: Streptomyces castelarensis sp. nov., comb. nov., Streptomyces himastatinicus sp. nov., Streptomyces mordarskii sp. nov., Streptomyces rapamycinicus sp. nov. and Streptomyces ruanii sp. nov. Int. J. Syst. Evol. Microbiol. 58: 1369-1378, 2008. PubMed 18523180

Vezina C, et al. Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J. Antibiot. 28: 721-726, 1975. PubMed: 1102508

Cross References

Nucleotide (GenBank) : AF007101 Streptomyces hygroscopicus putative pteridine-dependent dioxygenase, PKS modules 1,2,3 and 4, and putative regulatory protein genes, complete cds and putative hydroxylase gene, partial cds.

Nucleotide (GenBank) : EF408733 Streptomyces hygroscopicus strain NRRL B-5491 16S ribosomal RNA gene, partial sequence