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Difference between BT142 Homozygous and original BT142 cells
How is ATCC® ACS-1018 ™ BT142 mut/- (Homozygous) different from the original heterozygous BT142 cells?

ATCC® ACS-1018 ™ BT142 mut/- (Homozygous) cells have lost the wild-type IDH1 allele but retains the mutant allele.  The loss of the wild-type allele has been reported in vivo in patients and has been shown to be similar to phenotypically wild-type IDH, resulting in decreased 2-hydroxyglutarate production.
Date Created03/29/2013 01:08 PM
Date Updated03/27/2014 08:39 PM

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