ATCC does not MAP test cell lines although many murine lines have been screened for Ectromelia virus at the NIH and ATCC, and tests have been negative. [Buller, R.M.L., et al. (1987) Observations on the replication of Ectromelia virus in mouse-derived cell lines: Implications for epidemiology of mousepox. Lab. Animal Sci. 37:28].
Accordingly, if researchers intend to inoculate cell lines obtained from the ATCC into mice and return the mice to non-quarantined facilities with other animals, the inoculum should be MAP tested either in house or commercially elsewhere.
|Date Created||07/17/2012 07:10 PM
|Date Updated||03/27/2014 08:41 PM