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Endotoxin level and expiration date of serum
If serum has expired, does the endotoxin level increase as time goes by beyond the expiration date?

No, the endotoxin levels do not increase over time.  The product is sterile filtered and as long as it remains sterile the endotoxin will not increase. Endotoxins are toxins associated with certain bacteria and as long as bacteria are not growing and lysing there should be no increase in endotoxin level. The ATCC has tested serum bottles well beyond the official expiration date and found that the endotoxin levels have not increased over time.
Date Created07/17/2012 07:14 PM
Date Updated07/25/2012 05:22 PM

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