The B16 murine melanoma cell line originated in 1954. The tumor spontaneously arose in a C57BL/6J mouse at the Jackson Laboratories in Maine. The initial neoplastic lesion arose in the skin at the base of the ear. The tumor line was maintained at the Jackson Laboratories by continuous passage in vivo. Using the B16 melanoma line from the Jackson Laboratories, Dr. Isiah Fidler carefully documented the final disposition of the melanoma cells after i.v. injection in mice in 1970. There is no record of the sex of the originating mouse.
|Date Created||08/02/2019 10:27 AM
|Date Updated||08/02/2019 01:19 PM