Mycobacterium tuberculosis (Zopf) Lehmann and Neumann (ATCC® 25177)

Strain Designations: H37Ra  /  Type Strain: no  /  Biosafety Level: 2

Strain Designations H37Ra
Application
Media testing
Susceptibility testing
Emerging infectious disease research
Respiratory research
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Preceptrol® no
Genome Sequenced Strain

Mycobacterium tuberculosis H37Ra, complete genome.

Type Strain no
Comments
Attenuated
Genome sequenced strain
Name of Depositor CL Larson
U.S. Patent Number
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
References

McMurray DN, et al. Respiratory infection with attenuated Mycobacterium tuberculosis H37Ra in malnourished guinea pigs. Infect. Immun. 39: 793-799, 1983. PubMed: 6403460

Alsaadi AI, Smith DW. The fate of virulent and attenuated Mycobacteria in guinea pigs infected by the respiratory route. Am. Rev. Respir. Dis. 107: 1041-1046, 1973. PubMed: 4197232

European Pharmacopoeia Commission Mycobacterium tuberculosis. Strasbourg, France:European Pharmacopoeia Commission;European Pharmacopoeia EP 2.6.2, 1997

Quality Control for Commercially Prepared Microbiological Culture Media; Approved Standard - 3rd Edition. Wayne, PA. Clinical and Laboratory Standards Institute; CLSI M22-A3.

Li Z, et al. Rapid detection of Mycobacterium avium in stool samples from AIDS patients by immunomagnetic PCR. J. Clin. Microbiol. 34: 1903-1907, 1996. PubMed: 8818878

Voladri RK, et al. Recombinant expression and characterization of the major B-lactamase of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 42: 1375-1381, 1998. PubMed: 9624479

Hackbarth CJ, et al. Cloning and sequence analysis of a class A beta-lactamase from Mycobacterium tuberculosis H37Ra. Antimicrob. Agents Chemother. 41: 1182-1185, 1997. PubMed: 9145897

Cross References

Nucleotide (GenBank) : AX110247 Sequence 980 from Patent WO0123604.

Nucleotide (GenBank) : X70901 M.tuberculosis mce gene.

Nucleotide (GenBank) : U67924 class A beta-lactamase (blaA) gene sequence

Nucleotide (GenBank) : U24555 Mycobacterium tuberculosis 23S rRNA, partial sequence.

Nucleotide (GenBank) : CP000611 Mycobacterium tuberculosis H37Ra, complete genome.

Basic Documentation
FAQs
  1. ATCC item no. 25177 Biosafety Level
    ATCC® 25177 ™ is attenuated so is it is not virulent.
    Date Updated: 12/5/2013