Human mastadenovirus B (ATCC® VR-718)

Classification: Adenoviridae, Mastadenovirus, Human mastadenovirus B  /  Product Format: frozen

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Classification Adenoviridae, Mastadenovirus, Human mastadenovirus B
Deposited As Adenovirus type 35
Agent Human mastadenovirus B
Strain Holden
Common Name Human adenovirus B
Respiratory research
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions -70°C or colder
Acid and chloroform stable, partially heat-labile, no cationic stabilization. Group CF (hexon) titers of 1:16-1:128 expected.
Effect on Host
CPE, refractile rounding, clumping, and sloughing
Recommended Host
HEp-2 (ATCC® CCL-23™)
Growth Conditions Temperature: 37°C
Incubation: 2 to 4 days, a 5% CO2 in air atmosphere is recommended.
Recommendations for Infection: For best results cells should be 24 to 48 hours old and 80% - 90% confluent (not 100% confluent).
Effect on Host
CPE, refractile rounding, clumping, and sloughing
Name of Depositor JC Hierholzer
Source Lung and kidney tissues from 61-year-old woman who died with diffuse interstitial pneumonia

Hierholzer JC, et al. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121: 179-197, 1991. PubMed: 1759904

Ma Y, Mathews MB. Structure, function, and evolution of adenovirus-associated RNA: a phylogenetic approach. J. Virol. 70: 5083-5099, 1996. PubMed: 8764016

Myerowitz RL, et al. Fatal disseminated adenovirus infection in a renal transplant recipient. Am. J. Med. 59: 591-598, 1975. PubMed: 170822

Stalder H, et al. New human adenovirus (candidate adenovirus type 35) causing fatal disseminated infection in a renal transplant recipient. J. Clin. Microbiol. 6: 257-265, 1977. PubMed: 71305

Cross References

Nucleotide (GenBank) : U52572 Human adenovirus type 35 virus-associated RNA pre-terminal protein (pTP) and 52,55K protein genes, partial cds.

Notice: Necessary PermitsPermits

These permits may be required for shipping this product:

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
Basic Documentation