Avian leukosis (ATCC® VR-247)

Classification: Retrovirus, Avian Type C Retrovirus Group  /  Product Format: frozen

Classification Retrovirus, Avian Type C Retrovirus Group
Agent Avian leukosis
Strain RPL 12
Applications
Fibrosarcomas, nephromas, and endotheliomas are produced in chick embryos
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Isolation
Isolated from 223rd transplant passage of an avian lymphoid tumor
Product Format frozen
Storage Conditions -60°C
Comments
Strain RPL 12 produces 4 principal types of lesions in chickens: erythroblastosis, visceral lymphomatosis, osteopetrosis and hemangiomatosis. Fibrosarcomas, nephromas, and endotheliomas are produced in chick embryos (i.v.).
Avian Leukosis Virus is the Type Species of the Avian Type C Retrovirus Group. This preparation, of archival interest, is likely a mixture of viruses. Propagation in TC would introduce inapropriate selective pressure.
Effect on Host
Erythroblastosis or visceral lymphomatosis; death
Recommended Host
chicken (barrier reared), i.p. inoculation
chicken
Growth Conditions
Incubation: 4 months or longer
Effect on Host
Erythroblastosis or visceral lymphomatosis; death
Name of Depositor BR Burmester
Source
Isolated from 223rd transplant passage of an avian lymphoid tumor
References

Olson C. . Cancer Res. 1: 384, 1941.

Burmester B. Preparation Two. Cancer Res. 6: 189, 1946.